5BWN

Crystal Structure of SIRT3 with a H3K9 Peptide Containing a Myristoyl Lysine

Summary for 5BWN

• Entry DOI: 10.2210/pdb5bwn/pdb
• Related: 5BWL 5BWO 5BWP 5BWQ
• Descriptor: myristoyl H3K9 peptide, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ZINC ION, ... (4 entities in total)
• Functional Keywords: hydrolase, peptide-hydrolase complex, peptide/hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Mitochondrion matrix : Q9NTG7
• Total number of polymer chains: 2
• Total formula weight: 35770.40

Authors

Gai, W.,Liu, D. (deposition date: 2015-06-08, release date: 2016-07-13, Last modification date: 2023-11-08)

• Primary citation: Gai, W.,Li, H.,Jiang, H.,Long, Y.,Liu, D.; Crystal structures of SIRT3 reveal that the alpha 2-alpha 3 loop and alpha 3-helix affect the interaction with long-chain acyl lysine.; Febs Lett., 590:3019-3028, 2016; PubMed: 27501476; DOI: 10.1002/1873-3468.12345

Experimental method

X-RAY DIFFRACTION (1.942 Å)