5BWN

Crystal Structure of SIRT3 with a H3K9 Peptide Containing a Myristoyl Lysine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	myristoyl H3K9 peptide	polymer	10	1302.5	1	UniProt (by SIFTS) (Q6NXT2)	synthetic construct
2	B (A)	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	polymer	309	34402.4	1	UniProt (Q9NTG7) Pfam (PF02146)	Homo sapiens (Human)	hSIRT3,Regulatory protein SIR2 homolog 3,SIR2-like protein 3
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	D, E (B, A)	water	water		18.0	111	Chemie (HOH)

Sequence modifications

A: 118 - 399 (UniProt: Q9NTG7)

PDB	External Database	Details
Met 91	-	expression tag
Ala 92	-	expression tag
Ser 93	-	expression tag
Met 94	-	expression tag
Thr 95	-	expression tag
Gly 96	-	expression tag
Gly 97	-	expression tag
Gln 98	-	expression tag
Gln 99	-	expression tag
Met 100	-	expression tag
Gly 101	-	expression tag
Arg 102	-	expression tag
Gly 103	-	expression tag
Ser 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
Glu 111	-	expression tag
Asn 112	-	expression tag
Leu 113	-	expression tag
Tyr 114	-	expression tag
Phe 115	-	expression tag
Gln 116	-	expression tag
Gly 117	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35705.0
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	35770.4

*Water molecules are not included.