2KQE
| Second PBZ domain of human APLF protein in complex with ribofuranosyladenosine | 分子名称: | ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ... | 著者 | Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. | 登録日 | 2009-11-04 | 公開日 | 2010-01-19 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose). Nat.Struct.Mol.Biol., 17, 2010
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3JXC
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4UQH
| Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(3,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. | 分子名称: | (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(3,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE, ... | 著者 | Calvet, C.M, Vieira, D.F, Choi, J.Y, Cameron, M.D, Gut, J, Kellar, D, Siqueira-Neto, J.L, McKerrow, J.H, Roush, W.R, Podust, L.M. | 登録日 | 2014-06-23 | 公開日 | 2014-08-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | 4-Aminopyridyl-Based Cyp51 Inhibitors as Anti-Trypanosoma Cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency. J.Med.Chem., 57, 2014
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4V2U
| Apo-structure of alpha2,3-sialyltransferase from Pasteurella dagmatis | 分子名称: | SIALYLTRANSFERASE | 著者 | Pavkov-Keller, T, Schmoelzer, K, Czabany, T, Luley-Goedl, C, Ribitsch, D, Schwab, H, Nidetzky, B, Gruber, K. | 登録日 | 2014-10-15 | 公開日 | 2015-04-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Complete Switch from Alpha2,3- to Alpha2,6-Regioselectivity in Pasteurella Dagmatis Beta-D-Galactoside Sialyltransferase by Active-Site Redesign Chem.Commun.(Camb.), 51, 2015
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4W9A
| Crystal structure of Gamma-B Crystallin expressed in E. coli based on mRNA variant 2 | 分子名称: | Gamma-crystallin B | 著者 | Kudlinzki, D, Buhr, F, Linhard, V.L, Jha, S, Komar, A.A, Schwalbe, H. | 登録日 | 2014-08-27 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Two synonymous gene variants encode proteins with identical sequence, but different folding conformations. To Be Published
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4UV4
| Crystal structure of anti-FPR Fpro0165 Fab fragment | 分子名称: | FPRO0165 FAB | 著者 | Douthwaite, J.A, Sridharan, S, Huntington, C, Marwood, R, Hammersley, J, Hakulinen, J.K, Ek, M, Sjogren, T, Rider, D, Privezentzev, C, Seaman, J.C, Cariuk, P, Knights, V, Young, J, Wilkinson, T, Sleeman, M, Finch, D.K, Lowe, D.C, Vaughan, T.J. | 登録日 | 2014-08-04 | 公開日 | 2014-12-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Affinity Maturation of a Novel Antagonistic Human Monoclonal Antibody with a Long Vh Cdr3 Targeting the Class a Gpcr Formyl-Peptide Receptor 1. Mabs, 7, 2015
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4V0I
| Water Network Determines Selectivity for a Series of Pyrimidone Indoline Amide PI3KBeta Inhibitors over PI3K-Delta | 分子名称: | 2-[2-(2-METHYL-2,3-DIHYDRO-INDOL-1-YL)-2-OXO-ETHYL]-6-MORPHOLIN-4-YL-3H-PYRIMIDIN-4-ONE, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | 著者 | Robinson, D, Bertrand, T, Carry, J.C, Halley, F, Karlsson, A, Mathieu, M, Minoux, H, Perrin, M.A, Robert, B, Schio, L, Sherman, W. | 登録日 | 2014-09-16 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Differential Water Thermodynamics Determine Pi3K-Beta/Delta Selectivity for Solvent-Exposed Ligand Modifications. J.Chem.Inf.Model., 56, 2016
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4V38
| Apo-structure of alpha2,3-sialyltransferase variant 1 from Pasteurella dagmatis | 分子名称: | SIALYLTRANSFERASE | 著者 | Pavkov-Keller, T, Schmoelzer, K, Czabany, T, Luley-Goedl, C, Ribitsch, D, Schwab, H, Nidetzky, B, Gruber, K. | 登録日 | 2014-10-17 | 公開日 | 2015-04-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Complete Switch from Alpha2,3- to Alpha2,6-Regioselectivity in Pasteurella Dagmatis Beta-D-Galactoside Sialyltransferase by Active-Site Redesign Chem.Commun.(Camb.), 51, 2015
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3J5Y
| Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP | 分子名称: | 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ... | 著者 | des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2013-11-21 | 公開日 | 2013-12-25 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP. Nucleic Acids Res., 42, 2014
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3JCT
| Cryo-em structure of eukaryotic pre-60S ribosomal subunits | 分子名称: | 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | 著者 | Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N. | 登録日 | 2016-03-09 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes Nature, 534, 2016
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3JSR
| X-Ray structure of All0216 protein from Nostoc sp. PCC 7120 at the resolution 1.8A. Northeast Structural Genomics Consortium target NsR236 | 分子名称: | All0216 protein, POTASSIUM ION | 著者 | Kuzin, A.P, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-10 | 公開日 | 2009-09-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-Ray structure of All0216 protein from Nostoc sp. PCC 7120 at the resolution 1.8A To be Published
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3J9X
| A Virus that Infects a Hyperthermophile Encapsidates A-Form DNA | 分子名称: | DNA, coat protein | 著者 | DiMaio, F, Yu, X, Rensen, E, Krupovic, M, Prangishvili, D, Egelman, E. | 登録日 | 2015-03-21 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A virus that infects a hyperthermophile encapsidates A-form DNA. Science, 348, 2015
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4V1N
| Architecture of the RNA polymerase II-Mediator core transcription initiation complex | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | 登録日 | 2014-09-29 | 公開日 | 2015-02-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
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3K2Q
| Crystal structure of Pyrophosphate-dependent phosphofructokinase from Marinobacter aquaeolei, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MqR88 | 分子名称: | Pyrophosphate-dependent phosphofructokinase, SODIUM ION | 著者 | Seetharaman, J, Lew, S, Wang, D, Neely, H, Janjua, K, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-30 | 公開日 | 2009-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Pyrophosphate-dependent phosphofructokinase from Marinobacter aquaeolei, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MqR88 To be Published
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4V4Z
| 70S Thermus thermophilous ribosome functional complex with mRNA and E- and P-site tRNAs at 4.5A. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M. | 登録日 | 2006-06-27 | 公開日 | 2014-07-09 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (4.51 Å) | 主引用文献 | Structural basis for messenger RNA movement on the ribosome. Nature, 444, 2006
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4V5D
| Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA. | 分子名称: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2009-03-24 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome. Nat. Struct. Mol. Biol., 16, 2009
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3JCL
| Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer | 分子名称: | Spike glycoprotein | 著者 | Walls, A.C, Tortorici, M.A, Bosch, B.J, Frenz, B, Rottier, P.J.M, DiMaio, F, Rey, F.A, Veesler, D. | 登録日 | 2015-12-21 | 公開日 | 2016-02-03 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer. Nature, 531, 2016
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4V6T
| Structure of the bacterial ribosome complexed by tmRNA-SmpB and EF-G during translocation and MLD-loading | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Ramrath, D.J.F, Yamamoto, H, Rother, K, Wittek, D, Pech, M, Mielke, T, Loerke, J, Scheerer, P, Ivanov, P, Teraoka, Y, Shpanchenko, O, Nierhaus, K.H, Spahn, C.M.T. | 登録日 | 2012-01-27 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | The complex of tmRNA-SmpB and EF-G on translocating ribosomes. Nature, 485, 2012
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3K4E
| Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A | 分子名称: | RNA (5'-R(P*CP*UP*UP*GP*UP*AP*UP*AP*UP*A)-3'), mRNA-binding protein PUF3 | 著者 | Zhu, D, Stumpf, C.R, Krahn, J.M, Wickens, M, Hall, T.M.T. | 登録日 | 2009-10-05 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 106, 2009
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3K63
| X-ray structure of the PF04200 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. NESG target UuR17a. | 分子名称: | Conserved hypothetical membrane lipoprotein | 著者 | Vorobiev, S, Neely, H, Seetharaman, J, Lee, D, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-08 | 公開日 | 2009-10-20 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | X-ray structure of the PF04200 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. To be Published
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3JTC
| Importance of Mg2+ in the Ca2+-Dependent Folding of the gamma-Carboxyglutamic Acid Domains of Vitamin K-Dependent clotting and anticlotting Proteins | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endothelial protein C receptor, ... | 著者 | Bajaj, S.P, Vadivel, K, Agah, S, Cascio, D, Krishnaswamy, S, Esmon, C, Padmanabhan, K. | 登録日 | 2009-09-11 | 公開日 | 2011-04-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and Functional Studies of gamma-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium. J.Mol.Biol., 425, 2013
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4V0R
| DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH | 分子名称: | FORMIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D. | 登録日 | 2014-09-18 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication. Plos Pathog., 11, 2015
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3JXB
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4V1O
| Architecture of the RNA polymerase II-Mediator core transcription initiation complex | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | 著者 | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | 登録日 | 2014-09-29 | 公開日 | 2015-02-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
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3JCE
| Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4) | 分子名称: | 16S ribosomal RNA, 23 ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y. | 登録日 | 2015-12-01 | 公開日 | 2016-01-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome Nat. Struct. Mol. Biol., 23, 2016
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