Structure of the TRPA1 ion channel determined by electron cryo-microscopy

Summary for 3J9P

EMDB information6267
DescriptorMaltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera (1 entity in total)
Functional Keywordstrpa1, trp, transient, potential, receptor, ion channel, membrane protein, transport protein
Biological sourceEscherichia coli, Homo sapiens (bacteria, human)
Total number of polymer chains4
Total molecular weight690302.25
Paulsen, C.E.,Armache, J.-P.,Gao, Y.,Cheng, Y.,Julius, D. (deposition date: 2015-02-14, release date: 2015-04-08, Last modification date: 2018-07-18)
Primary citation
Paulsen, C.E.,Armache, J.P.,Gao, Y.,Cheng, Y.,Julius, D.
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 520:511-517, 2015
PubMed: 25855297 (PDB entries with the same primary citation)
DOI: 10.1038/nature14367
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers25 1.6% 2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-10-21