3J9P

Structure of the TRPA1 ion channel determined by electron cryo-microscopy

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (D, A, B, C)	Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera	polymer	1528	172575.6	4	UniProt (P0AEX9) UniProt (O75762) Pfam (PF01547) Pfam (PF00023) Pfam (PF00520)	Escherichia coli Homo sapiens (bacteria human)	Ankyrin-like with transmembrane domains protein 1, Transformation-sensitive protein p120, Transient Receptor Potential Ankyrin 1 ion channel

Sequence modifications

D, A, B, C: -392 - -27 (UniProt: P0AEX9)

PDB	External Database	Details
Met -408	-	expression tag
Gly -407	-	expression tag
Ser -406	-	expression tag
Ser -405	-	expression tag
His -404	-	expression tag
His -403	-	expression tag
His -402	-	expression tag
His -401	-	expression tag
His -400	-	expression tag
His -399	-	expression tag
His -398	-	expression tag
His -397	-	expression tag
Gly -396	-	expression tag
Ser -395	-	expression tag
Ser -394	-	expression tag
Met -393	-	expression tag

D, A, B, C: 2 - 1119 (UniProt: O75762)

PDB	External Database	Details
Asn -26	-	linker
Ser -25	-	linker
Ser -24	-	linker
Ser -23	-	linker
Asn -22	-	linker
Asn -21	-	linker
Asn -20	-	linker
Asn -19	-	linker
Asn -18	-	linker
Asn -17	-	linker
Asn -16	-	linker
Asn -15	-	linker
Asn -14	-	linker
Asn -13	-	linker
Leu -12	-	linker
Gly -11	-	linker
Ile -10	-	linker
Glu -9	-	linker
Glu -8	-	linker
Asn -7	-	linker
Leu -6	-	linker
Tyr -5	-	linker
Phe -4	-	linker
Gln -3	-	linker
Gly -2	-	linker
Ala -1	-	linker
Gly 0	-	linker
Ser 1	-	linker
Asp 966	Glu 966	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	690302.2
All*	Total formula weight	690302.2

*Water molecules are not included.