3JV4

Crystal structure of the dimerization domains p50 and RelB

Summary for 3JV4

Entry DOI	10.2210/pdb3jv4/pdb
Related	3jtc 3juz 3jv0 3jv5 3jv6
Descriptor	Transcription factor RelB, Nuclear factor NF-kappa-B p105 subunit (2 entities in total)
Functional Keywords	nf-kb protein, heterodimer, relb and p50, activator, nucleus, phosphoprotein, transcription, transcription regulation, ank repeat, apoptosis, dna-binding, s-nitrosylation
Biological source	Mus musculus (mouse) More
Cellular location	Nucleus: Q04863 Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus: P25799
Total number of polymer chains	6
Total formula weight	74375.96
Authors	Vu, D.,Huang, D.B.,Ghosh, G. (deposition date: 2009-09-15, release date: 2010-11-24, Last modification date: 2024-02-21)
Primary citation	Vu, D.,Huang, D.B.,Vemu, A.,Ghosh, G. A structural basis for selective dimerization by NF-kappa B RelB. J.Mol.Biol., 425:1934-1945, 2013 Cited by PubMed: 23485337 DOI: 10.1016/j.jmb.2013.02.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.15 Å)

Structure validation