7S04
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Acinetobacter baumannii in complex with FR900098, NADPH, and a magnesium ion | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[ethanoyl(hydroxy)amino]propylphosphonic acid, MAGNESIUM ION, ... | 著者 | Noble, S.M, Ball, H.S, Couch, R.D. | 登録日 | 2021-08-28 | 公開日 | 2021-11-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Characterization and Inhibition of 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase: A Promising Drug Target in Acinetobacter baumannii and Klebsiella pneumoniae . Acs Infect Dis., 7, 2021
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6M9B
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8WG7
| Cryo-EM structures of peptide free and Gs-coupled GLP-1R | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Cong, Z.T, Zhao, F.H, Li, Y, Luo, G, Zhou, Q.T, Yang, D.H, Wang, M.W. | 登録日 | 2023-09-20 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins. Cell Discov, 10, 2024
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1BFC
| BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT | 分子名称: | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, BASIC FIBROBLAST GROWTH FACTOR | 著者 | Faham, S, Rees, D.C. | 登録日 | 1995-12-12 | 公開日 | 1996-04-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Heparin structure and interactions with basic fibroblast growth factor. Science, 271, 1996
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8VRR
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8WG8
| Cryo-EM structures of peptide free and Gs-coupled GCGR | 分子名称: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Cong, Z.T, Zhao, F.H, Li, Y, Luo, G, Zhou, Q.T, Yang, D.H, Wang, M.W. | 登録日 | 2023-09-20 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins. Cell Discov, 10, 2024
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6VJK
| Streptavidin mutant M88 (N49C/A86C) | 分子名称: | BIOTIN, Streptavidin | 著者 | Marangoni, J.M, Wu, S.C, Fogen, D, Wong, S.L, Ng, K.K.S. | 登録日 | 2020-01-16 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Engineering a disulfide-gated switch in streptavidin enables reversible binding without sacrificing binding affinity. Sci Rep, 10, 2020
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6PPH
| Kaposi's sarcoma-associated herpesvirus (KSHV), C1 penton vertex register, CATC-binding structure | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Gong, D, Dai, X, Jih, J, Liu, Y.T, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2019-07-06 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. Cell, 178, 2019
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8HFM
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8OFM
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8BDG
| Tubulin-taxane-2b complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Prota, A.E, Lucena-Agell, D, Ma, Y, Estevez-Gallego, J, Li, S, Bargsten, K, Altmann, K.H, Gaillard, N, Kamimura, S, Muehlethaler, T, Gago, F, Oliva, M.A, Steinmetz, M.O, Fang, W.S, Diaz, J.F. | 登録日 | 2022-10-19 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insight into the stabilization of microtubules by taxanes. Elife, 12, 2023
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8HFO
| Crystal Structure of Mycobacterium smegmatis MshC in Complex with Compound 7d | 分子名称: | CALCIUM ION, L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, N-[(3M)-3-(thiophen-2-yl)benzene-1-sulfonyl]-L-cysteinamide, ... | 著者 | Pang, L, Weeks, S.D, Strelkov, S.V. | 登録日 | 2022-11-11 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides. Int J Mol Sci, 23, 2022
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7PLM
| CryoEM reconstruction of pyruvate ferredoxin oxidoreductase (PFOR) in anaerobic conditions | 分子名称: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | 著者 | Cherrier, M.V, Vernede, X, Fenel, D, Martin, L, Arragain, B, Neumann, E, Fontecilla Camps, J.C, Schoehn, G, Nicolet, Y. | 登録日 | 2021-08-31 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Oxygen-Sensitive Metalloprotein Structure Determination by Cryo-Electron Microscopy. Biomolecules, 12, 2022
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8HFN
| Crystal Structure of Mycobacterium smegmatis MshC in Complex with Compound 7b | 分子名称: | CALCIUM ION, L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, N-[(3M)-3-(6-methoxypyridin-3-yl)benzene-1-sulfonyl]-L-cysteinamide, ... | 著者 | Pang, L, Weeks, S.D, Strelkov, S.V. | 登録日 | 2022-11-11 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides. Int J Mol Sci, 23, 2022
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5MI9
| Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E | 分子名称: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A. | 登録日 | 2016-11-27 | 公開日 | 2017-12-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors. Sci Adv, 4, 2018
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1B6L
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4 | 分子名称: | 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE, RETROPEPSIN, SULFATE ION | 著者 | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | 登録日 | 1999-01-17 | 公開日 | 2000-01-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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5MKC
| Crystal structure of the RrgA Jo.In complex | 分子名称: | CALCIUM ION, Cell wall surface anchor family protein (Jo),Cell wall surface anchor family protein (In), NICKEL (II) ION, ... | 著者 | Bonnet, J, Cartannaz, J, Tourcier, G, Contreras-Martel, C, Kleman, J.P, Fenel, D, Schoehn, G, Morlot, C, Vernet, T, Di Guilmi, A.M. | 登録日 | 2016-12-03 | 公開日 | 2017-03-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin. Sci Rep, 7, 2017
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7ZEH
| Human cytosolic 5' nucleotidase IIIB in complex with 3,4-diF-Bn7Guanine | 分子名称: | 1,2-ETHANEDIOL, 7-methylguanosine phosphate-specific 5'-nucleotidase, D-ribulose, ... | 著者 | Kubacka, D, Kozarski, M, Baranowski, M.R, Wojcik, R, Jemielity, J, Kowalska, J, Basquin, J. | 登録日 | 2022-03-31 | 公開日 | 2022-05-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism. Pharmaceuticals, 15, 2022
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1AO5
| MOUSE GLANDULAR KALLIKREIN-13 (PRORENIN CONVERTING ENZYME) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLANDULAR KALLIKREIN-13 | 著者 | Timm, D.E. | 登録日 | 1997-07-16 | 公開日 | 1997-10-15 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The crystal structure of the mouse glandular kallikrein-13 (prorenin converting enzyme) Protein Sci., 6, 1997
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4XYK
| Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics Consortium Target HR9275 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... | 著者 | Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2015-02-02 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
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6YKO
| Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11a | 分子名称: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2020-04-06 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
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6B67
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7UEM
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1BBC
| STRUCTURE OF RECOMBINANT HUMAN RHEUMATOID ARTHRITIC SYNOVIAL FLUID PHOSPHOLIPASE A2 AT 2.2 ANGSTROMS RESOLUTION | 分子名称: | PHOSPHOLIPASE A2 | 著者 | Wery, J.-P, Schevitz, R.W, Clawson, D.K, Bobbitt, J.L, Dow, E.R, Gamboa, G, Goodsonjunior, T, Hermann, R.B, Kramer, R.M, Mcclure, D.B, Mihelich, E.D, Putnam, J.E, Sharp, J.D, Stark, D.H, Teater, C, Warrick, M.W, Jones, N.D. | 登録日 | 1992-05-04 | 公開日 | 1993-10-31 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 A resolution. Nature, 352, 1991
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6VSC
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