6B67

Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA)

Summary for 6B67

• Entry DOI: 10.2210/pdb6b67/pdb
• Descriptor: Protein phosphatase 1A, cyclic peptide c(MpSIpYVA), CALCIUM ION, ... (4 entities in total)
• Functional Keywords: phosphatase, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 101947.46

Authors

Dyda, F.,Kosek, D. (deposition date: 2017-10-01, release date: 2018-04-11, Last modification date: 2023-11-15)

• Primary citation: Debnath, S.,Kosek, D.,Tagad, H.D.,Durell, S.R.,Appella, D.H.,Acevedo, R.,Grishaev, A.,Dyda, F.,Appella, E.,Mazur, S.J.; A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity.; J. Biol. Chem., 293:7993-8008, 2018; PubMed: 29602904; DOI: 10.1074/jbc.RA117.001213

Experimental method

X-RAY DIFFRACTION (2.2 Å)