6B67
Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Protein phosphatase 1A | polymer | 296 | 32845.9 | 3 | UniProt (P35813) Pfam (PF00481) In PDB | Homo sapiens (Human) | Protein phosphatase 2C isoform alpha,PP2C-alpha,Protein phosphatase IA |
| 2 | D, E, F | cyclic peptide c(MpSIpYVA) | polymer | 7 | 1003.0 | 3 | synthetic construct | ||
| 3 | A, B, C | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 4 | water | water | 18.0 | 633 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 297 (UniProt: P35813)
| PDB | External Database | Details |
|---|---|---|
| Glu 146 | Asp 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 101546.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 400.8 | |
| All* | Total formula weight | 101947.5 |
