8HFO

Crystal Structure of Mycobacterium smegmatis MshC in Complex with Compound 7d

Summary for 8HFO

Entry DOI	10.2210/pdb8hfo/pdb
Related	8HFM 8HFN
Descriptor	L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, N-[(3M)-3-(thiophen-2-yl)benzene-1-sulfonyl]-L-cysteinamide, ZINC ION, ... (5 entities in total)
Functional Keywords	rossmann fold, ligase, inhibitor
Biological source	Mycolicibacterium smegmatis MC2 155
Total number of polymer chains	1
Total formula weight	45956.55
Authors	Pang, L.,Weeks, S.D.,Strelkov, S.V. (deposition date: 2022-11-11, release date: 2022-12-07, Last modification date: 2023-10-25)
Primary citation	Pang, L.,Lenders, S.,Osipov, E.M.,Weeks, S.D.,Rozenski, J.,Piller, T.,Cappoen, D.,Strelkov, S.V.,Van Aerschot, A. Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides. Int J Mol Sci, 23:-, 2022 Cited by PubMed: 36499418 DOI: 10.3390/ijms232315095 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation