2QFB
| Crystal structure of the regulatory domain of human RIG-I with bound Zn | Descriptor: | Probable ATP-dependent RNA helicase DDX58, ZINC ION | Authors: | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | Deposit date: | 2007-06-27 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I. Mol.Cell, 29, 2008
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2QFD
| Crystal structure of the regulatory domain of human RIG-I with bound Hg | Descriptor: | MERCURY (II) ION, Probable ATP-dependent RNA helicase DDX58 | Authors: | Cui, S, Lammens, A, Lammens, K, Hopfner, K.P. | Deposit date: | 2007-06-27 | Release date: | 2008-02-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I. Mol.Cell, 29, 2008
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3EIK
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3OCI
| Crystal structure of TBP (TATA box binding protein) | Descriptor: | 1,2-ETHANEDIOL, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | Authors: | Cui, S, Wollmann, P, Moldt, M, Hopfner, K.-P. | Deposit date: | 2010-08-10 | Release date: | 2011-07-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP. Nature, 475, 2011
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7YC2
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5GMQ
| Structure of MERS-CoV RBD in complex with a fully human antibody MCA1 | Descriptor: | 1,2-ETHANEDIOL, MCA1 heavy chain, MCA1 light chain, ... | Authors: | Chen, C, Wang, J.M, Zou, T.T, Gao, X.P, Cui, S, Jin, Q. | Deposit date: | 2016-07-15 | Release date: | 2017-05-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset. J. Infect. Dis., 215, 2017
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8GQC
| Crystal structure of the SARS-unique domain (SUD) of SARS-CoV-2 (1.35 angstrom resolution) | Descriptor: | Papain-like protease nsp3 | Authors: | Qin, B, Li, Z, Aumonier, S, Wang, M, Cui, S. | Deposit date: | 2022-08-30 | Release date: | 2023-07-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Identification of the SARS-unique domain of SARS-CoV-2 as an antiviral target. Nat Commun, 14, 2023
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8K88
| Structure of procaryotic Ago | Descriptor: | DNA (41-mer), DNA/RNA (21-mer), MAGNESIUM ION, ... | Authors: | Gao, X, Sun, D, Cui, S, Wang, Y. | Deposit date: | 2023-07-29 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural Basis of prokaryotic Argonaute System To Be Published
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8K87
| Dimer structure of procaryotic Ago | Descriptor: | DNA (41-mer), MAGNESIUM ION, Piwi domain protein, ... | Authors: | Gao, X, Sun, D, Cui, S, Wang, Y. | Deposit date: | 2023-07-29 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Basis of prokaryotic Argonaute System To Be Published
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5GRB
| Crystal structure of 2C helicase from enterovirus 71 (EV71) bound with ATPgammaS | Descriptor: | EV71 2C ATPase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ZINC ION | Authors: | Guan, H.X, Tian, J, Qin, B, Wojdyla, J, Wang, M.T, Cui, S. | Deposit date: | 2016-08-09 | Release date: | 2017-05-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Crystal structure of 2C helicase from enterovirus 71 SCI ADV, 3, 2017
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5GQ1
| Crystal structure of 2C helicase from enterovirus 71 (EV71) | Descriptor: | Genome polyprotein, PHOSPHATE ION, ZINC ION | Authors: | Guan, H.X, Tian, J, Qin, B, Wojdyla, J, Wang, M.T, Cui, S. | Deposit date: | 2016-08-05 | Release date: | 2017-05-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.493 Å) | Cite: | Crystal structure of 2C helicase from enterovirus 71 SCI ADV, 3, 2017
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5H7Z
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5H7Y
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2W4R
| Crystal structure of the regulatory domain of human LGP2 | Descriptor: | MERCURY (II) ION, PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, SULFATE ION | Authors: | Pippig, D.A, Hellmuth, J.C, Cui, S, Kirchhofer, A, Lammens, K, Lammens, A, Schmidt, A, Rothenfusser, S, Hopfner, K.P. | Deposit date: | 2008-12-01 | Release date: | 2009-02-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA. Nucleic Acids Res., 37, 2009
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5KWB
| Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 1.9 angstrom, molecular replacement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Spike glycoprotein, ... | Authors: | Guan, H, Wojdyla, J.A, Wang, M, Cui, S. | Deposit date: | 2016-07-17 | Release date: | 2017-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1 Nat Commun, 8, 2017
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4I2L
| New HIV entry inhibitor MTSFT/T23 complex | Descriptor: | GP41, inhibitor MTSFT | Authors: | Yao, X, Chong, H.H, Waltersperger, S, Wang, M.T, He, Y.X, Cui, S. | Deposit date: | 2012-11-22 | Release date: | 2014-01-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.426 Å) | Cite: | Potent antiviral activity of the novel HIV entry inhibitor MTSFT To be Published
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7CMD
| Crystal structure of the SARS-CoV-2 PLpro with GRL0617 | Descriptor: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, ZINC ION | Authors: | Gao, X, Cui, S. | Deposit date: | 2020-07-27 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structure of SARS-CoV-2 papain-like protease. Acta Pharm Sin B, 11, 2021
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7CJD
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7CDW
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5GNB
| Crystal Structure of the Receptor Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1 (HKU1 1A-CTD, 2.3 angstrom, native-SAD phasing) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Guan, H, Wojdyla, J.A, Wang, M, Cui, S. | Deposit date: | 2016-07-20 | Release date: | 2017-06-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1 Nat Commun, 8, 2017
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3K1K
| Green fluorescent protein bound to enhancer nanobody | Descriptor: | Enhancer, Green Fluorescent Protein | Authors: | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | Deposit date: | 2009-09-28 | Release date: | 2009-12-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Modulation of protein properties in living cells using nanobodies Nat.Struct.Mol.Biol., 17, 2010
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3VGX
| Structure of gp41 T21/Cp621-652 | Descriptor: | ACETIC ACID, Envelope glycoprotein gp160, GLYCEROL | Authors: | Yao, X, Waltersperger, S, Wang, M, Cui, S. | Deposit date: | 2011-08-22 | Release date: | 2012-04-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652. J.Biol.Chem., 287, 2012
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3VH7
| Structure of HIV-1 gp41 NHR/fusion inhibitor complex P21 | Descriptor: | CP32M, Envelope glycoprotein gp160, MAGNESIUM ION | Authors: | Yao, X, Waltersperger, S, Wang, M.T, Cui, S. | Deposit date: | 2011-08-23 | Release date: | 2012-06-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.019 Å) | Cite: | Structural basis of potent and broad HIV-1 fusion inhibitor CP32M J.Biol.Chem., 287, 2012
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3VTP
| HIV fusion inhibitor MT-C34 | Descriptor: | Transmembrane protein gp41 | Authors: | Yao, X, Waltersperger, S, Wang, M, Cui, S. | Deposit date: | 2012-06-02 | Release date: | 2012-08-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The M-T hook structure is critical for design of HIV-1 fusion inhibitors. J.Biol.Chem., 287, 2012
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3VGY
| Structure of HIV-1 gp41 NHR/fusion inhibitor complex P321 | Descriptor: | CP32M, Envelope glycoprotein gp160, SULFATE ION | Authors: | Yao, X, Waltersperger, S, Wang, M.T, Cui, S. | Deposit date: | 2011-08-22 | Release date: | 2012-06-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.034 Å) | Cite: | Structural basis of potent and broad HIV-1 fusion inhibitor CP32M J.Biol.Chem., 287, 2012
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