Crystal structure of the SARS-CoV-2 PLro C111S mutant

Summary for 7CJD

DescriptorReplicase polyprotein 1ab, ZINC ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsproteinase;drug target;, hydrolase
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains4
Total molecular weight147975.08
Gao, X.,Cui, S. (deposition date: 2020-07-10, release date: 2020-09-02, Last modification date: 2020-09-23)
Primary citation
Gao, X.,Qin, B.,Chen, P.,Zhu, K.,Hou, P.,Wojdyla, J.A.,Wang, M.,Cui, S.
Crystal structure of SARS-CoV-2 papain-like protease.
Acta Pharm Sin B, 2020
PubMed: 32895623 (PDB entries with the same primary citation)
DOI: 10.1016/j.apsb.2020.08.014
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28214 0.4% 2.3% 10.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-30