7CJD
Crystal structure of the SARS-CoV-2 PLpro C111S mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, A, B, C | Non-structural protein 3 | polymer | 325 | 36912.8 | 4 | UniProt (P0DTD1) Pfam (PF08715) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | pp1ab,ORF1ab polyprotein,nsp3,PL2-PRO,Papain-like protease,Papain-like proteinase,PL-PRO,Replicase polyprotein 1ab |
2 | D, A, B, C | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
D, A, B, C: 1 - 318 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Ser 111 | Cys 1674 | engineered mutation |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
His 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 147651.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 323.7 | |
All* | Total formula weight | 147975.1 |