2W4R
Crystal structure of the regulatory domain of human LGP2
Summary for 2W4R
Entry DOI | 10.2210/pdb2w4r/pdb |
Descriptor | PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, MERCURY (II) ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | innate immunity, immune response, nucleotide-binding, coiled coil, atp-binding, polymorphism, double-strand rna binding protein, helicase, hydrolase, cytoplasm, rna-binding |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q96C10 |
Total number of polymer chains | 4 |
Total formula weight | 66137.29 |
Authors | Pippig, D.A.,Hellmuth, J.C.,Cui, S.,Kirchhofer, A.,Lammens, K.,Lammens, A.,Schmidt, A.,Rothenfusser, S.,Hopfner, K.P. (deposition date: 2008-12-01, release date: 2009-02-24, Last modification date: 2023-12-13) |
Primary citation | Pippig, D.A.,Hellmuth, J.C.,Cui, S.,Kirchhofer, A.,Lammens, K.,Lammens, A.,Schmidt, A.,Rothenfusser, S.,Hopfner, K.P. The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA. Nucleic Acids Res., 37:2014-, 2009 Cited by PubMed: 19208642DOI: 10.1093/NAR/GKP059 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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