3VGY

Structure of HIV-1 gp41 NHR/fusion inhibitor complex P321

Summary for 3VGY

Related3VGX 3VH7
DescriptorEnvelope glycoprotein gp160, CP32M, SULFATE ION, ... (4 entities in total)
Functional Keywords6-helix bundle, membrane fusion inhibition, membrane protein-inhibitor complex, membrane protein/inhibitor
Biological sourceHuman immunodeficiency virus type 1 (HIV-1)
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Cellular locationTransmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein P03375
Total number of polymer chains2
Total molecular weight10805.15
Authors
Yao, X.,Waltersperger, S.,Wang, M.T.,Cui, S. (deposition date: 2011-08-22, release date: 2012-06-13, Last modification date: 2013-06-26)
Primary citation
Yao, X.,Chong, H.,Zhang, C.,Qiu, Z.,Qin, B.,Han, R.,Waltersperger, S.,Wang, M.T.,He, Y.,Cui, S.
Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287:26618-26629, 2012
PubMed: 22679024 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M112.381079
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.034 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2641102.8%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 3vgy
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Molmil generated image of 3vgy
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3vgy.pdb1.gz [82.4 KB])