2GF3
 
 | | Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution. | | Descriptor: | 2-FUROIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Chen, Z, Trickey, P, Jorns, M.S, Mathews, F.S. | | Deposit date: | 2006-03-21 | | Release date: | 2007-02-06 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.
TO BE PUBLISHED
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2GP5
 | | Crystal structure of catalytic core domain of jmjd2A complexed with alpha-Ketoglutarate | | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, Jumonji domain-containing protein 2A, ... | | Authors: | Chen, Z, Zang, J, Whetstine, J, Hong, X, Davrazou, F, Kutateladze, T.G, Simpson, M, Dai, S, Hagman, J, Shi, Y, Zhang, G. | | Deposit date: | 2006-04-16 | | Release date: | 2006-05-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
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2GP3
 | | Crystal structure of the catalytic core domain of jmjd2a | | Descriptor: | FE (II) ION, Jumonji domain-containing protein 2A, ZINC ION | | Authors: | Chen, Z, Zang, J, Whetstine, J, Hong, X, Davrazou, F, Kutateladze, T.G, Simpson, M, Dai, S, Hagman, J, Shi, Y, Zhang, G. | | Deposit date: | 2006-04-16 | | Release date: | 2006-05-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
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5H5Z
 | | Crystal structure of bony fish MHC class I, peptide and B2m II | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, peptide chain | | Authors: | Chen, Z, Zhang, N, Qi, J, Li, X, Chen, R, Wang, Z, Gao, F.G, Xia, C. | | Deposit date: | 2016-11-10 | | Release date: | 2017-11-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The Mechanism of beta 2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish.
Iscience, 23, 2020
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7EQB
 | | Crystal structure of the dimerization domain of ZEN-4 | | Descriptor: | Kinesin-like protein, SULFATE ION | | Authors: | Chen, Z, Pan, H. | | Deposit date: | 2021-05-01 | | Release date: | 2022-04-13 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.103 Å) | | Cite: | Mechanistic insights into central spindle assembly mediated by the centralspindlin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7EQC
 | | Crystal structure of the mini-centralspindlin complex | | Descriptor: | CYtoKinesis defect, Kinesin-like protein | | Authors: | Chen, Z, Pan, H. | | Deposit date: | 2021-05-01 | | Release date: | 2022-04-13 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanistic insights into central spindle assembly mediated by the centralspindlin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6AZE
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6BC0
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6BC1
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6DMP
 | | De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks | | Descriptor: | Designed orthogonal protein DHD13_XAAA_A, Designed orthogonal protein DHD13_XAAA_B | | Authors: | Chen, Z, Flores-Solis, D, Sgourakis, N.G, Baker, D. | | Deposit date: | 2018-06-05 | | Release date: | 2018-12-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
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3KZ1
 | | Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ... | | Authors: | Chen, Z, Sternweis, P.C, Sprang, S.R. | | Deposit date: | 2009-12-07 | | Release date: | 2010-04-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
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3SGZ
 | | High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole. | | Descriptor: | 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 2 | | Authors: | Chen, Z, Vignaud, C, Jaafar, A, Gueritte, F, Guenard, D, Lederer, F, Mathews, F.S. | | Deposit date: | 2011-06-15 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design.
Biochimie, 94, 2012
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8I3G
 | | Crystal structure of Eaf3-Eaf7 complex | | Descriptor: | Chromatin modification-related protein EAF3, Chromatin modification-related protein EAF7 | | Authors: | Chen, Z, Xu, C. | | Deposit date: | 2023-01-17 | | Release date: | 2023-05-31 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular basis for Eaf3-mediated assembly of Rpd3S and NuA4.
Cell Discov, 9, 2023
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8I3F
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3ODX
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3ODO
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3ODW
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3P6A
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5X3E
 | | kinesin 6 | | Descriptor: | IODIDE ION, Kinesin-like protein, SULFATE ION | | Authors: | Chen, Z, Guan, R, Zhang, L. | | Deposit date: | 2017-02-04 | | Release date: | 2017-04-19 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin
Nat Commun, 8, 2017
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5EWU
 | | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A | | Descriptor: | BENZOIC ACID, MAGNESIUM ION, Magnesium-chelatase subunit ChlH, ... | | Authors: | Chen, Z, Zhang, X, Liu, Y, Jiang, L. | | Deposit date: | 2015-11-21 | | Release date: | 2016-12-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A
To Be Published
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1AHT
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1C6V
 | | SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H) | | Descriptor: | PROTEIN (SIU89134), PROTEIN (SIV INTEGRASE) | | Authors: | Chen, Z, Yan, Y, Munshi, S, Li, Y, Zruygay-Murphy, J, Xu, B, Witmer, M, Felock, P, Wolfe, A, Sardana, V, Emini, E.A, Hazuda, D, Kuo, L.C. | | Deposit date: | 1999-12-21 | | Release date: | 2000-12-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
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8EOG
 | | Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine | | Descriptor: | (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. | | Deposit date: | 2022-10-03 | | Release date: | 2023-05-24 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | EMC chaperone-Ca V structure reveals an ion channel assembly intermediate.
Nature, 619, 2023
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8EOI
 | | Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Chen, Z, Mondal, A, Abderemane-Ali, F, Minor, D.L. | | Deposit date: | 2022-10-03 | | Release date: | 2023-05-24 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | EMC chaperone-Ca V structure reveals an ion channel assembly intermediate.
Nature, 619, 2023
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7YAG
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 1 | | Descriptor: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | Authors: | Chen, Z, Watanabe, S, Inaba, K. | | Deposit date: | 2022-06-28 | | Release date: | 2023-03-22 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
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