8EOI
Structure of a human EMC:human Cav1.2 channel complex in GDN detergent
Summary for 8EOI
Entry DOI | 10.2210/pdb8eoi/pdb |
EMDB information | 28376 |
Descriptor | ER membrane protein complex subunit 1, Voltage-dependent L-type calcium channel subunit beta-3, ER membrane protein complex subunit 4, ... (14 entities in total) |
Functional Keywords | endoplasmic reticulum membrane protein complex, voltage-gated calcium channel, holdase, biogenesis, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 11 |
Total formula weight | 483944.81 |
Authors | Chen, Z.,Mondal, A.,Abderemane-Ali, F.,Minor, D.L. (deposition date: 2022-10-03, release date: 2023-05-24, Last modification date: 2023-07-26) |
Primary citation | Chen, Z.,Mondal, A.,Abderemane-Ali, F.,Jang, S.,Niranjan, S.,Montano, J.L.,Zaro, B.W.,Minor Jr., D.L. EMC chaperone-Ca V structure reveals an ion channel assembly intermediate. Nature, 619:410-419, 2023 Cited by PubMed: 37196677DOI: 10.1038/s41586-023-06175-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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