8EOI
Structure of a human EMC:human Cav1.2 channel complex in GDN detergent
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ER membrane protein complex subunit 1 | polymer | 973 | 109598.4 | 1 | UniProt (Q8N766) Pfam (PF13360) Pfam (PF07774) | Homo sapiens (human) | |
| 2 | B (B) | ER membrane protein complex subunit 2 | polymer | 291 | 34250.8 | 1 | UniProt (Q15006) Pfam (PF22890) | Homo sapiens (human) | Tetratricopeptide repeat protein 35,TPR repeat protein 35 |
| 3 | C (C) | ER membrane protein complex subunit 3 | polymer | 258 | 29722.6 | 1 | UniProt (Q9P0I2) Pfam (PF01956) | Homo sapiens (human) | Transmembrane protein 111 |
| 4 | D (E) | ER membrane protein complex subunit 5 | polymer | 101 | 11425.1 | 1 | UniProt (Q8N4V1) Pfam (PF10270) | Homo sapiens (human) | Membrane magnesium transporter 1,Transmembrane protein 32 |
| 5 | E (F) | ER membrane protein complex subunit 6 | polymer | 100 | 11014.0 | 1 | UniProt (Q9BV81) Pfam (PF07019) | Homo sapiens (human) | Transmembrane protein 93 |
| 6 | F (G) | ER membrane protein complex subunit 7 | polymer | 116 | 13151.0 | 1 | UniProt (Q9NPA0) Pfam (PF09430) | Homo sapiens (human) | |
| 7 | G (H) | ER membrane protein complex subunit 8 | polymer | 208 | 23578.8 | 1 | UniProt (O43402) Pfam (PF03665) | Homo sapiens (human) | Neighbor of COX4,Protein FAM158B |
| 8 | H (I) | ER membrane protein complex subunit 10 | polymer | 157 | 17003.9 | 1 | UniProt (Q5UCC4) Pfam (PF21203) | Homo sapiens (human) | Hematopoietic signal peptide-containing membrane domain-containing protein 1 |
| 9 | I (K) | Voltage-dependent L-type calcium channel subunit alpha-1C | polymer | 1550 | 176678.8 | 1 | UniProt (Q13936) Pfam (PF00520) Pfam (PF08016) Pfam (PF16905) Pfam (PF08763) | Homo sapiens (human) | Calcium channel,L type,alpha-1 polypeptide,isoform 1,cardiac muscle,Voltage-gated calcium channel subunit alpha Cav1.2 |
| 10 | J (J) | Voltage-dependent L-type calcium channel subunit beta-3 | polymer | 324 | 36692.1 | 1 | UniProt (P54286) Pfam (PF12052) Pfam (PF00625) | Oryctolagus cuniculus (rabbit) | CAB3,Calcium channel voltage-dependent subunit beta 3 |
| 11 | K (D) | ER membrane protein complex subunit 4 | polymer | 170 | 18790.1 | 1 | UniProt (Q5J8M3) Pfam (PF06417) | Homo sapiens (human) | Cell proliferation-inducing gene 17 protein,Transmembrane protein 85 |
| 12 | L, M, N (L, M, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 13 | O (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 14 | P (K) | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 1 | Chemie (9Z9) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 481905.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 766.0 | |
| All* | Total formula weight | 483944.8 |
