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PDB: 731 results

5JN9
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BU of 5jn9 by Molmil
Crystal structure for the complex of human carbonic anhydrase IV and ethoxyzolamide
Descriptor: 6-ethoxy-1,3-benzothiazole-2-sulfonamide, ACETATE ION, Carbonic anhydrase 4, ...
Authors:Chen, Z, Waheed, A, Di Cera, E, Sly, W.S.
Deposit date:2016-04-29
Release date:2017-05-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur. Biophys. J., 47, 2018
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
3ODX
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BU of 3odx by Molmil
Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-12
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODO
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BU of 3odo by Molmil
Crystal Structure of the DH/PH Domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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BU of 3odw by Molmil
Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3P6A
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BU of 3p6a by Molmil
Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant)
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-10-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
6AZE
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BU of 6aze by Molmil
Crystal Structure of the BPTF PHD-bromodomain module bound to H3KC4me3 methyl lysine analog
Descriptor: ALA-ARG-THR-ML3-GLN-THR, Nucleosome-remodeling factor subunit BPTF, ZINC ION
Authors:Chen, Z, Ruthenburg, A.J.
Deposit date:2017-09-11
Release date:2018-09-19
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Quantitative and structural assessment of methyllysine analog engagement by cognate binding proteins reveals decrements that can impact qualitative experiment interpretation
To be published
7ENN
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BU of 7enn by Molmil
The structure of ALC1 bound to the nucleosome
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromodomain-helicase-DNA-binding protein 1-like, ...
Authors:Chen, Z.C, Chen, K.J, Wang, L.
Deposit date:2021-04-18
Release date:2021-07-14
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
3NBJ
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BU of 3nbj by Molmil
Crystal Structure of Y305F mutant of the copper amine oxidase from Hansenula polymorpha expressed in yeast
Descriptor: COPPER (II) ION, PHOSPHATE ION, Peroxisomal primary amine oxidase
Authors:Chen, Z, Datta, S, DuBois, J.L, Klinman, J.P, Mathews, F.S.
Deposit date:2010-06-03
Release date:2010-08-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mutation at a strictly conserved, active site tyrosine in the copper amine oxidase leads to uncontrolled oxygenase activity.
Biochemistry, 49, 2010
3DXU
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BU of 3dxu by Molmil
The crystal structure of core JMJD2D complexed with FE and N-oxalylglycine
Descriptor: FE (II) ION, GLYCEROL, JmjC domain-containing histone demethylation protein 3D, ...
Authors:Chen, Z, Zhang, G.
Deposit date:2008-07-25
Release date:2009-07-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of Core Jmjd2D
To be Published
3DXT
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BU of 3dxt by Molmil
Crystal structure of the catalytic core domain of JMJD2D
Descriptor: GLYCEROL, JmjC domain-containing histone demethylation protein 3D, SULFATE ION, ...
Authors:Chen, Z, Zhang, G.
Deposit date:2008-07-25
Release date:2009-10-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the catalytic core domain of jmjd2d
To be Published
7VDT
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BU of 7vdt by Molmil
The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ...
Authors:Chen, Z.C, Chen, K.J, Yuan, J.J.
Deposit date:2021-09-07
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
2PXJ
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BU of 2pxj by Molmil
The complex structure of JMJD2A and monomethylated H3K36 peptide
Descriptor: FE (II) ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ...
Authors:Chen, Z, Zang, J, Kappler, J, Hong, X, Crawford, F, Zhang, G.
Deposit date:2007-05-14
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
5VF3
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BU of 5vf3 by Molmil
Bacteriophage T4 isometric capsid
Descriptor: Capsid vertex protein gp24, Highly immunogenic outer capsid protein, Major capsid protein, ...
Authors:Chen, Z, Sun, L, Zhang, Z, Fokine, A, Padilla-Sanchez, V, Hanein, D, Jiang, W, Rossmann, M.G, Rao, V.B.
Deposit date:2017-04-06
Release date:2017-09-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the bacteriophage T4 isometric head at 3.3- angstrom resolution and its relevance to the assembly of icosahedral viruses.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6GY5
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BU of 6gy5 by Molmil
Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Death-associated protein kinase 1, ...
Authors:Chen, Z, Hozjan, V, Strain-Damerell, C, Williams, E, Wang, D, Cooper, C.D.O, Sanvitale, C.E, Fairhead, M, Carpenter, E.P, Pike, A.C.W, Krojer, T, Srikannathasan, V, Sorrell, F, Johansson, C, Mathea, S, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2018-06-28
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.086 Å)
Cite:Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Structure, 27, 2019
7EQC
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BU of 7eqc by Molmil
Crystal structure of the mini-centralspindlin complex
Descriptor: CYtoKinesis defect, Kinesin-like protein
Authors:Chen, Z, Pan, H.
Deposit date:2021-05-01
Release date:2022-04-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanistic insights into central spindle assembly mediated by the centralspindlin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EQB
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BU of 7eqb by Molmil
Crystal structure of the dimerization domain of ZEN-4
Descriptor: Kinesin-like protein, SULFATE ION
Authors:Chen, Z, Pan, H.
Deposit date:2021-05-01
Release date:2022-04-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Mechanistic insights into central spindle assembly mediated by the centralspindlin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
5EWU
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BU of 5ewu by Molmil
Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A
Descriptor: BENZOIC ACID, MAGNESIUM ION, Magnesium-chelatase subunit ChlH, ...
Authors:Chen, Z, Zhang, X, Liu, Y, Jiang, L.
Deposit date:2015-11-21
Release date:2016-12-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of the Arabidopsis thaliana C-terminal Chlh at 1.25A
To Be Published
6L5M
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BU of 6l5m by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6L5N
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BU of 6l5n by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state
Descriptor: MAGNESIUM ION, Nucleolar RNA helicase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (2.242 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6L5L
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BU of 6l5l by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at apo state
Descriptor: MAGNESIUM ION, Nucleolar RNA helicase 2
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6L5O
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BU of 6l5o by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
7VVY
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BU of 7vvy by Molmil
TRA module of NuA4
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
Authors:Chen, Z, Qu, K.
Deposit date:2021-11-09
Release date:2022-08-10
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
7VVU
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BU of 7vvu by Molmil
NuA4 HAT module bound to the nucleosome
Descriptor: CARBOXYMETHYL COENZYME *A, Chromatin modification-related protein EAF6, Chromatin modification-related protein YNG2, ...
Authors:Chen, Z, Qu, K.
Deposit date:2021-11-09
Release date:2022-08-10
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022

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