5JN9
Crystal structure for the complex of human carbonic anhydrase IV and ethoxyzolamide
Summary for 5JN9
Entry DOI | 10.2210/pdb5jn9/pdb |
Related | 5JN8 5JNA 5JNC 5JND |
Descriptor | Carbonic anhydrase 4, ZINC ION, 6-ethoxy-1,3-benzothiazole-2-sulfonamide, ... (7 entities in total) |
Functional Keywords | carbonic anhydrase, lyase, inhibitor binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 124007.76 |
Authors | Chen, Z.,Waheed, A.,Di Cera, E.,Sly, W.S. (deposition date: 2016-04-29, release date: 2017-05-03, Last modification date: 2023-09-27) |
Primary citation | Mickeviciute, A.,Timm, D.D.,Gedgaudas, M.,Linkuviene, V.,Chen, Z.,Waheed, A.,Michailoviene, V.,Zubriene, A.,Smirnov, A.,Capkauskaite, E.,Baranauskiene, L.,Jachno, J.,Revuckiene, J.,Manakova, E.,Grazulis, S.,Matuliene, J.,Di Cera, E.,Sly, W.S.,Matulis, D. Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47:271-290, 2018 Cited by PubMed: 28975383DOI: 10.1007/s00249-017-1256-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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