6L6G
| Crystal structure of SeMet_Lpg0189 | Descriptor: | GLYCEROL, Uncharacterized protein Lpg0189 | Authors: | Ge, H, Chen, X. | Deposit date: | 2019-10-29 | Release date: | 2019-11-27 | Last modified: | 2020-01-15 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold. Biochem.Biophys.Res.Commun., 521, 2020
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1WM8
| Solution Structure of BmP03 from the Venom of Scorpion Buthus martensii Karsch, 10 structures | Descriptor: | Neurotoxin BmP03 | Authors: | Wu, H, He, F, Li, Y, Wu, G, Cao, C, Chen, X. | Deposit date: | 2004-07-05 | Release date: | 2004-07-27 | Last modified: | 2018-04-18 | Method: | SOLUTION NMR | Cite: | Three-Dimensional Structure of BmP03 from Venom of Scorpion Buthus martensii Karsch Acta Chim.Sinica, 58, 2000
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1WM7
| Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch, 9 structures | Descriptor: | Neurotoxin BmP01 | Authors: | Wu, G, Li, Y, Wei, D, He, F, Jiang, S, Hu, G, Wu, H, Chen, X. | Deposit date: | 2004-07-05 | Release date: | 2004-07-27 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution Structure of BmP01 from the Venom of Scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 276, 2000
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5X0T
| Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8 | Descriptor: | 6H8 Fab fragment heavy chain, 6H8 Fab fragment light chain, Basigin | Authors: | Lin, P, Zhang, M.-Y, Ye, S, Chen, X, Yu, X.-L, Zhang, R.-G, Zhu, P, Chen, Z.-N. | Deposit date: | 2017-01-23 | Release date: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody To Be Published
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5X4G
| Crystal structure of Fab fragment of anti-CD147 monoclonal antibody 6H8 | Descriptor: | 6H8 Fab heavy chain, 6H8 Fab light chain | Authors: | Lin, P, Zhang, M.-Y, Chen, X, Ye, S, Yu, X.-L, Zhang, R.-G, Zhu, P, Chen, Z.-N. | Deposit date: | 2017-02-13 | Release date: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody To Be Published
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7V9M
| Cryo-EM structure of the GHRH-bound human GHRHR splice variant 1 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Chen, X, Yang, D.H, Wang, M.W. | Deposit date: | 2021-08-26 | Release date: | 2021-10-20 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Constitutive signal bias mediated by the human GHRHR splice variant 1. Proc.Natl.Acad.Sci.USA, 118, 2021
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7VI6
| Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila | Descriptor: | Beta-N-acetylhexosaminidase, CHLORIDE ION, MAGNESIUM ION | Authors: | Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M. | Deposit date: | 2021-09-26 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation Biochem.Biophys.Res.Commun., 589, 2022
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7VI7
| Crystal structure of GH3 beta-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila in complex with GlcNAc | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ... | Authors: | Qian, K, Yang, W, Chen, X, Wang, Y, Zhang, M, Wang, M. | Deposit date: | 2021-09-26 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Functional and structural characterization of a GH3 beta-N-acetylhexosaminidase from Akkermansia muciniphila involved in mucin degradation Biochem.Biophys.Res.Commun., 589, 2022
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6IZK
| Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | Descriptor: | CHLORIDE ION, IMIDAZOLE, L(+)-TARTARIC ACID, ... | Authors: | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | Deposit date: | 2018-12-19 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus To Be Published
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7CK6
| Protein translocase of mitochondria | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | Authors: | Yang, M, Wang, W, Zhang, L, Chen, X. | Deposit date: | 2020-07-15 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Atomic structure of human TOM core complex. Cell Discov, 6, 2020
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6JQF
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7DL2
| Cryo-EM structure of human TSC complex | Descriptor: | Hamartin, Isoform 7 of Tuberin, TBC1 domain family member 7, ... | Authors: | Yang, H, Yu, Z, Chen, X, Li, J, Li, N, Cheng, J, Gao, N, Yuan, H, Ye, D, Guan, K, Xu, Y. | Deposit date: | 2020-11-25 | Release date: | 2020-12-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural insights into TSC complex assembly and GAP activity on Rheb. Nat Commun, 12, 2021
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6LS4
| A novel anti-tumor agent S-40 in complex with tubulin | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | Authors: | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | Deposit date: | 2020-01-17 | Release date: | 2021-01-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Cancer Lett., 495, 2020
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6M4Q
| Cytochrome P450 monooxygenase StvP2 substrate-free structure | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | Deposit date: | 2020-03-08 | Release date: | 2020-08-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
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7EKA
| crystal structure of epigallocatechin binding with alpha-lactalbumin | Descriptor: | 2-(3,4,5-TRIHYDROXY-PHENYL)-CHROMAN-3,5,7-TRIOL, Alpha-lactalbumin | Authors: | Ma, J, Yao, Q, Chen, X, Zang, J. | Deposit date: | 2021-04-05 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Weak Binding of Epigallocatechin to alpha-Lactalbumin Greatly Improves Its Stability and Uptake by Caco-2 Cells. J.Agric.Food Chem., 69, 2021
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6M4P
| Cytochrome P450 monooxygenase StvP2 substrate-bound structure | Descriptor: | 6-methoxy-streptovaricin C, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | Deposit date: | 2020-03-08 | Release date: | 2020-08-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
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6IR2
| Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM2 at 1.4 Angstron resolution | Descriptor: | MCherry fluorescent protein, mCherry's nanobody LaM2 | Authors: | Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X. | Deposit date: | 2018-11-09 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.393 Å) | Cite: | Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry. Protein Sci., 30, 2021
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6IR1
| Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM4 at 1.9 Angstron resolution | Descriptor: | MCherry fluorescent protein, mCherry's nanobody LaM4 | Authors: | Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X. | Deposit date: | 2018-11-09 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.919 Å) | Cite: | Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry. Protein Sci., 30, 2021
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