5Z8Z
 
 | | BRD4 Bromodomain 1 with an inhibitor | | 分子名称: | 6-[(3S)-3-azanylpiperidin-1-yl]sulfonyl-1-ethyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 | | 著者 | Xiao, S, Chen, S, Chen, H. | | 登録日 | 2018-02-01 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | BRD4 Bromodomain 1 with an inhibitor
To Be Published
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7EVP
 | | Cryo-EM structure of the Gp168-beta-clamp complex | | 分子名称: | Beta sliding clamp, Sliding clamp inhibitor | | 著者 | Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. | | 登録日 | 2021-05-21 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel.
Nucleic Acids Res., 49, 2021
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6KH1
 | | Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | | 分子名称: | FE (III) ION, Ferritin, NICKEL (II) ION | | 著者 | Gu, C, Chen, H, Wang, Y, Zhang, T, Whang, H, Zhao, G. | | 登録日 | 2019-07-12 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
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6KH3
 | | Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | | 分子名称: | FE (III) ION, Ferritin, NICKEL (II) ION | | 著者 | Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G. | | 登録日 | 2019-07-12 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
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6KH5
 | | Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | | 分子名称: | FE (III) ION, Ferritin, NICKEL (II) ION | | 著者 | Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G. | | 登録日 | 2019-07-12 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | | 主引用文献 | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
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6KH4
 | | Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | | 分子名称: | FE (III) ION, Ferritin, NICKEL (II) ION | | 著者 | Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G. | | 登録日 | 2019-07-12 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
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4DCE
 | | Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor | | 分子名称: | (3S)-N-(4-methylbenzyl)-1-{2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}piperidine-3-carboxamide, ALK tyrosine kinase receptor | | 著者 | Whittington, D.A, Epstein, L.F, Chen, H. | | 登録日 | 2012-01-17 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors.
J.Med.Chem., 55, 2012
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5ZND
 | | 8-mer nanotube derived from 24-mer rHuHF nanocage | | 分子名称: | Ferritin heavy chain | | 著者 | Wang, W.M, Wang, L.L, Zang, J.C, Chen, H, Zhao, G.H, Wang, H.F. | | 登録日 | 2018-04-09 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings.
J. Am. Chem. Soc., 140, 2018
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6IPO
 | | Ferritin mutant C90A/C102A/C130A/D144C | | 分子名称: | Ferritin heavy chain, MAGNESIUM ION | | 著者 | Zang, J, Chen, H, Zhang, X, Zhao, G. | | 登録日 | 2018-11-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
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6IPP
 | | Non-native ferritin 8-mer mutant-C90A/C102A/C130A/D144C | | 分子名称: | FE (III) ION, Ferritin heavy chain | | 著者 | Zang, J, Chen, H, Zhou, K, Zhao, G. | | 登録日 | 2018-11-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | | 主引用文献 | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
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6J7G
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6J4M
 | | Thermal treated soybean seed H-2 ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Zhang, X, Zang, J, Chen, H, Zhou, K, Zhao, G. | | 登録日 | 2019-01-09 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface.
Rsc Adv, 9, 2019
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6JPS
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6IPC
 | | Non-native human ferritin 8-mer | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ferritin heavy chain | | 著者 | Zang, J.C, Chen, H, Zhao, G. | | 登録日 | 2018-11-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.443 Å) | | 主引用文献 | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
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6IPQ
 | | Non-native ferritin 8-mer mutant-C90A/C102A/C130A | | 分子名称: | Ferritin heavy chain, MAGNESIUM ION | | 著者 | Zang, J, Chen, H, Wang, Y, Zhao, G. | | 登録日 | 2018-11-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.103 Å) | | 主引用文献 | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
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6J4J
 | | soybean seed H-2 ferritin | | 分子名称: | Ferritin, MAGNESIUM ION | | 著者 | Zhang, X, Zang, J, Chen, H, Zhao, G. | | 登録日 | 2019-01-09 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Thermostability of protein nanocages: the effect of natural extra peptide on the exterior surface.
Rsc Adv, 9, 2019
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6K98
 | | Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family | | 分子名称: | GH12 beta-1, 4-endoglucanase | | 著者 | Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, yingguo, B, Bin, Y. | | 登録日 | 2019-06-14 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | | 主引用文献 | Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
To Be Published
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6K9D
 | | glycoside hydrolase family 12 (GH12) englucanase | | 分子名称: | GH12 beta-1, 4-endoglucanase | | 著者 | Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, Yingguo, B, Bin, Y. | | 登録日 | 2019-06-14 | | 公開日 | 2020-06-17 | | 実験手法 | X-RAY DIFFRACTION (1.505 Å) | | 主引用文献 | Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
To Be Published
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6JYW
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7V6G
 | | Structure of Candida albicans Fructose-1,6-bisphosphate aldolase mutation C157S with CN39 | | 分子名称: | 1,2-ETHANEDIOL, Fructose-bisphosphate aldolase, ZINC ION, ... | | 著者 | Cao, H, Huang, Y, Chen, H, Wan, C, Ren, Y, Wan, J. | | 登録日 | 2021-08-20 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | | 主引用文献 | Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis.
J.Med.Chem., 65, 2022
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7WPY
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8HD5
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1PQN
 | | dominant negative human hDim1 (hDim1 1-128) | | 分子名称: | Spliceosomal U5 snRNP-specific 15 kDa protein | | 著者 | Zhang, Y.Z, Cheng, H, Gould, K.L, Golemis, E.A, Roder, H. | | 登録日 | 2003-06-18 | | 公開日 | 2003-08-26 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, stability and function of hDim1 investigated by NMR, circular
dichroism and mutational analysis
Biochemistry, 42, 2003
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8GTN
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6C3N
 | | Crystal structure of BCL6 BTB domain in complex with compound 7CC5 | | 分子名称: | B-cell lymphoma 6 protein, N-(2-phenylethyl)-N'-pyridin-3-ylthiourea | | 著者 | Linhares, B, Cheng, H, Xue, F, Cierpicki, T. | | 登録日 | 2018-01-10 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.53170586 Å) | | 主引用文献 | Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.
J.Med.Chem., 61, 2018
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