3J9M
| Structure of the human mitochondrial ribosome (class 1) | Descriptor: | 12S rRNA, 16S rRNA, E-site tRNA, ... | Authors: | Amunts, A, Brown, A, Toots, J, Scheres, S.H, Ramakrishnan, V. | Deposit date: | 2015-02-08 | Release date: | 2015-04-15 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ribosome. The structure of the human mitochondrial ribosome. Science, 348, 2015
|
|
3ZR7
| Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators | Descriptor: | 2-CHLORO-N-[[4-(3,5-DIMETHYLISOXAZOL-4-YL)PHENYL]METHYL]-1,4-DIMETHYL-1H-PYRAZOLE-4-SULFONAMIDE, GLYCEROL, PROGESTERONE RECEPTOR, ... | Authors: | Lusher, S.J, Raaijmakers, H.C.A, Vu-Pham, D, Dechering, K, Wai Lam, T, Brown, A.R, Hamilton, N.M, Nimz, O, Azevedo, R, McGuire, R, Oubrie, A, de Vlieg, J. | Deposit date: | 2011-06-15 | Release date: | 2011-08-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators. J. Biol. Chem., 286, 2011
|
|
3J7A
| Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | Authors: | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | Deposit date: | 2014-06-03 | Release date: | 2014-07-16 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
|
|
3J79
| Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | Deposit date: | 2014-06-02 | Release date: | 2014-07-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
|
|
3J6B
| Structure of the yeast mitochondrial large ribosomal subunit | Descriptor: | 21S ribosomal RNA, 54S ribosomal protein IMG1, mitochondrial, ... | Authors: | Amunts, A, Brown, A, Bai, X.C, Llacer, J.L, Hussain, T, Emsley, P, Long, F, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | Deposit date: | 2014-01-22 | Release date: | 2014-04-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the yeast mitochondrial large ribosomal subunit. Science, 343, 2014
|
|
3E82
| Crystal structure of a putative oxidoreductase from Klebsiella pneumoniae | Descriptor: | CHLORIDE ION, Putative oxidoreductase | Authors: | Eswaramoorthy, S, Mohammad, M.B, Thomas, C.A, Brown, A.C, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-08-19 | Release date: | 2008-08-26 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of a putative oxidoreductase from Klebsiella pneumoniae To be Published
|
|
5UMD
| Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Wong, W, Bai, X.-C, Brown, A, Scheres, S, Baum, J. | Deposit date: | 2017-01-27 | Release date: | 2017-03-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nat Microbiol, 2, 2017
|
|
7JU4
| Radial spoke 2 stalk, IDAc, and N-DRC attached with doublet microtubule | Descriptor: | 28 kDa inner dynein arm light chain, axonemal, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | Deposit date: | 2020-08-19 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
|
|
7JTS
| Stalk of radial spoke 1 attached with doublet microtubule from Chlamydomonas reinhardtii | Descriptor: | Calmodulin, Dynein 8 kDa light chain, flagellar outer arm, ... | Authors: | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | Deposit date: | 2020-08-18 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
|
|
7JTK
| Radial spoke 1 isolated from Chlamydomonas reinhardtii | Descriptor: | Cytochrome b5 heme-binding domain-containing protein, Dynein 8 kDa light chain, flagellar outer arm, ... | Authors: | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | Deposit date: | 2020-08-17 | Release date: | 2020-12-16 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
|
|
2QJ3
| Mycobacterium tuberculosis FabD | Descriptor: | Malonyl CoA-acyl carrier protein transacylase, NICKEL (II) ION | Authors: | Ghadbane, H, Brown, A.K, Kremer, L, Besra, G.S, Futterer, K. | Deposit date: | 2007-07-06 | Release date: | 2007-09-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT). Acta Crystallogr.,Sect.F, 63, 2007
|
|
1G27
| CRYSTAL STRUCTURE OF E.COLI POLYPEPTIDE DEFORMYLASE COMPLEXED WITH THE INHIBITOR BB-3497 | Descriptor: | 2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEXANOIC ACID (1-DIMETHYLCARBAMOYL-2,2-DIMETHYL-PROPYL)-AMIDE, NICKEL (II) ION, POLYPEPTIDE DEFORMYLASE | Authors: | Clements, J.M, Beckett, P, Brown, A, Catlin, C, Lobell, M, Palan, S, Thomas, W, Whittaker, M, Baker, P.J, Rodgers, H.F, Barynin, V, Rice, D.W, Hunter, M.G. | Deposit date: | 2000-10-17 | Release date: | 2001-10-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor. Antimicrob.Agents Chemother., 45, 2001
|
|
1G2A
| THE CRYSTAL STRUCTURE OF E.COLI PEPTIDE DEFORMYLASE COMPLEXED WITH ACTINONIN | Descriptor: | ACTINONIN, NICKEL (II) ION, POLYPEPTIDE DEFORMYLASE | Authors: | Clements, J.M, Beckett, P, Brown, A, Catlin, C, Lobell, M, Palan, S, Thomas, W, Whittaker, M, Baker, P.J, Rodgers, H.F, Barynin, V, Rice, D.W, Hunter, M.G. | Deposit date: | 2000-10-18 | Release date: | 2001-10-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor. Antimicrob.Agents Chemother., 45, 2001
|
|
8OS5
| Crystal structure of the Factor XII heavy chain reveals an interlocking dimer with a FnII to kringle domain interaction | Descriptor: | Coagulation factor XII-Mie | Authors: | Li, C, Saleem, M, Kaira, B.G, Brown, A, Wilson, C, Philippou, H, Emsley, J. | Deposit date: | 2023-04-18 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136, 2020
|
|
5NX2
| Crystal structure of thermostabilised full-length GLP-1R in complex with a truncated peptide agonist at 3.7 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucagon-like peptide 1 receptor, ... | Authors: | Rappas, M, Jazayeri, A, Brown, A.J.H, Kean, J, Errey, J.C, Robertson, N, Fiez-Vandal, C, Andrews, S.P, Congreve, M, Bortolato, A, Mason, J.S, Baig, A.H, Teobald, I, Dore, A.S, Weir, M, Cooke, R.M, Marshall, F.H. | Deposit date: | 2017-05-09 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Crystal structure of the GLP-1 receptor bound to a peptide agonist. Nature, 546, 2017
|
|