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PDB: 273 件

3HH8
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Crystal Structure and metal binding properties of the lipoprotein MtsA
分子名称: FE (III) ION, Metal ABC transporter substrate-binding lipoprotein
著者Baker, E.N, Baker, H.M, Sun, X, Ye, Q.-Y.
登録日2009-05-15
公開日2009-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes.
Biochemistry, 48, 2009
2ACT
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CRYSTALLOGRAPHIC REFINEMENT OF THE STRUCTURE OF ACTINIDIN AT 1.7 ANGSTROMS RESOLUTION BY FAST FOURIER LEAST-SQUARES METHODS
分子名称: ACTINIDIN PRECURSOR, AMMONIUM ION
著者Baker, E.N.
登録日1979-11-27
公開日1980-03-07
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystallographic Refinement of the Structure of Actinidin at 1.7 Angstroms Resolution by Fast Fourier Least-Squares Methods
Acta Crystallogr.,Sect.A, 36, 1980
5LO4
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Engineering protein stability with atomic precision in a monomeric miniprotein
分子名称: PPa-CH3
著者Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
登録日2016-08-08
公開日2017-05-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
5LO2
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Engineering protein stability with atomic precision in a monomeric miniprotein
分子名称: PPaTyr
著者Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
登録日2016-08-08
公開日2017-05-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
5LO3
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Engineering protein stability with atomic precision in a monomeric miniprotein
分子名称: PPaOMe
著者Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N.
登録日2016-08-08
公開日2017-05-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Engineering protein stability with atomic precision in a monomeric miniprotein.
Nat. Chem. Biol., 13, 2017
1AZC
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STRUCTURE OF APO-AZURIN FROM ALCALIGENES DENITRIFICANS AT 1.8 ANGSTROMS RESOLUTION
分子名称: AZURIN, COPPER (II) ION, SULFATE ION
著者Baker, E.N, Shepard, W.E.B, Kingston, R.L.
登録日1992-12-16
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of apo-azurin from Alcaligenes denitrificans at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
1AZB
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STRUCTURE OF APO-AZURIN FROM ALCALIGENES DENITRIFICANS AT 1.8 ANGSTROMS RESOLUTION
分子名称: AZURIN, COPPER (II) ION, SULFATE ION
著者Baker, E.N, Shepard, W.E.B.
登録日1992-12-16
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of apo-azurin from Alcaligenes denitrificans at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
1LFG
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Structure of diferric human lactoferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Baker, E.N, Anderson, B.F, Haridas, M.
登録日1992-02-05
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human diferric lactoferrin refined at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 51, 1995
1AIZ
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STRUCTURE OF APO-AZURIN FROM ALCALIGENES DENITRIFICANS AT 1.8 ANGSTROMS RESOLUTION
分子名称: AZURIN, CADMIUM ION, SULFATE ION
著者Baker, E.N, Anderson, B.F, Blackwell, K.A.
登録日1993-11-11
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of apo-azurin from Alcaligenes denitrificans at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
1B0L
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RECOMBINANT HUMAN DIFERRIC LACTOFERRIN
分子名称: CARBONATE ION, FE (III) ION, PROTEIN (LACTOFERRIN)
著者Baker, E.N, Jameson, G.B, Sun, X.
登録日1998-11-11
公開日1999-11-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of recombinant human lactoferrin expressed in Aspergillus awamori.
Acta Crystallogr.,Sect.D, 55, 1999
2AZA
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BU of 2aza by Molmil
STRUCTURE OF AZURIN FROM ALCALIGENES DENITRIFICANS. REFINEMENT AT 1.8 ANGSTROMS RESOLUTION AND COMPARISON OF THE TWO CRYSTALLOGRAPHICALLY INDEPENDENT MOLECULES
分子名称: AZURIN, COPPER (II) ION, SULFATE ION
著者Baker, E.N, Norris, G.E.
登録日1986-10-14
公開日1987-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of azurin from Alcaligenes denitrificans refinement at 1.8 A resolution and comparison of the two crystallographically independent molecules.
J.Mol.Biol., 203, 1988
2FYF
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Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis
分子名称: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
著者Coulibaly, F, Lassalle, E, Baker, E.N, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-02-07
公開日2007-01-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
4W1U
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Crystal structure of Rv3557c/KstR2, a transcriptional repressor involved in cholesterol metabolism in Mycobacterium tuberculosis
分子名称: HTH-type transcriptional repressor KstR2
著者Dawes, S.S, Kendall, S.K, Baker, E.N, Lott, J.S.
登録日2014-08-13
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.875 Å)
主引用文献Crystal structure of Rv3557c/KstR2, a transcriptional repressor involved in cholesterol metabolism in Mycobacterium tuberculosis.
To Be Published
4P0D
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The T6 backbone pilin of serotype M6 Streptococcus pyogenes has a modular three-domain structure decorated with variable loops and extensions
分子名称: CALCIUM ION, IODIDE ION, Trypsin-resistant surface T6 protein
著者Young, P.G, Moreland, N.J, Loh, J.M, Bell, A, Atatoa-Carr, P, Proft, T, Baker, E.N.
登録日2014-02-20
公開日2014-08-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Conservation, Variability, and Immunogenicity of the T6 Backbone Pilin of Serotype M6 Streptococcus pyogenes.
Infect.Immun., 82, 2014
3HAM
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Structure of the gentamicin-APH(2")-IIa complex
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Aminoglycoside phosphotransferase, GLYCEROL
著者Young, P.G, Baker, E.N, Vakulenko, S.B, Smith, C.A.
登録日2009-05-02
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily.
J.Bacteriol., 191, 2009
3GLE
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Crystal Structure of the Major Pilin from Streptococcus pyogenes N168A mutant
分子名称: Pilin
著者Kang, H.J, Baker, E.N.
登録日2009-03-12
公開日2009-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenes
To be Published
2YPQ
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3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J.
登録日2012-10-31
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis.
J.Mol.Biol., 425, 2013
2G5F
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The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase
分子名称: COG0147: Anthranilate/para-aminobenzoate synthases component I, GLYCEROL, IMIDAZOLE, ...
著者Harrison, A.J, Lott, J.S, Yu, M, Ramsay, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC)
登録日2006-02-22
公開日2006-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase
J.Bacteriol., 188, 2006
3KGF
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The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2009-10-29
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3HPX
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Crystal structure of Mycobacterium tuberculosis LeuA active site domain 1-425 (truncation mutant delta:426-644)
分子名称: 2-isopropylmalate synthase, GLYCEROL, NICKEL (II) ION
著者Koon, N, Squire, C.J, Baker, E.N.
登録日2009-06-05
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Removal of the C-terminal regulatory domain of alpha-isopropylmalate synthase disrupts functional substrate binding
Biochemistry, 51, 2012
6O04
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M.tb MenD IntII bound with Inhibitor
分子名称: (1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid, 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ...
著者Johnston, J.M, Bashiri, G, Bulloch, E.M, Jirgis, E.M.N, Nigon, L.V, Chuang, H, Baker, E.N.
登録日2019-02-15
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
6O0J
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M.tb MenD with ThDP and Inhibitor bound
分子名称: 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ACETATE ION, ...
著者Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Nigon, L.V, Chuang, H, Ho, N.A.T, Baker, E.N.
登録日2019-02-16
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
6O0N
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M.tb MenD with Inhibitor
分子名称: 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
著者Johnston, J.M, Ho, N.A.T, Bashiri, G, Bulloch, E.M, Nigon, L.V, Jirgis, E.M.N, Baker, E.N.
登録日2019-02-16
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
6O0G
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M.tb MenD bound to Intermediate I and Inhibitor
分子名称: 1,4-dihydroxy-2-naphthoic acid, 2-OXOGLUTARIC ACID, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ...
著者Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Chuang, H, Nigon, L.V, Baker, E.N.
登録日2019-02-16
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
3NV8
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The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free)
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Parker, E.J, Jameson, G.B, Jiao, W, Hutton, R.H, Webby, C.J, Baker, E.N, Baker, H.M.
登録日2010-07-08
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010

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