2G5F
The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase
Summary for 2G5F
Entry DOI | 10.2210/pdb2g5f/pdb |
Descriptor | COG0147: Anthranilate/para-aminobenzoate synthases component I, PYRUVIC ACID, IMIDAZOLE, ... (5 entities in total) |
Functional Keywords | beta sandwhich, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, biosynthetic protein |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 196121.72 |
Authors | Harrison, A.J.,Lott, J.S.,Yu, M.,Ramsay, R.,Baker, E.N.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2006-02-22, release date: 2006-09-05, Last modification date: 2023-11-15) |
Primary citation | Harrison, A.J.,Gardenborg, T.,Yu, M.,Middleditch, M.,Ramsay, R.J.,Baker, E.N.,Lott, J.S. The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase J.Bacteriol., 188:6081-6091, 2006 Cited by PubMed: 16923875DOI: 10.1128/JB.00338-06 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report