2G5F
The structure of MbtI from Mycobacterium Tuberculosis, the first enzyme in the synthesis of Mycobactin, reveals it to be a salicylate synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | COG0147: Anthranilate/para-aminobenzoate synthases component I | polymer | 450 | 48779.2 | 4 | UniProt (Q7D785) Pfam (PF00425) UniProt (by SIFTS) (P9WFX1) In PDB | Mycobacterium tuberculosis | MbtI Salicylate synthase |
| 2 | A, B | PYRUVIC ACID | non-polymer | 88.1 | 2 | Chemie (PYR) | |||
| 3 | A, C, D | IMIDAZOLE | non-polymer | 69.1 | 4 | Chemie (IMD) | |||
| 4 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 993 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 450 (UniProt: Q7D785)
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 195116.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1005.0 | |
| All* | Total formula weight | 196121.7 |
