2P5B
 
 | | The complex structure of JMJD2A and trimethylated H3K36 peptide | | 分子名称: | FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ... | | 著者 | Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y. | | 登録日 | 2007-03-14 | | 公開日 | 2007-06-12 | | 最終更新日 | 2013-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
|
|
7WWQ
 | | Crystal structure of human Ufd1-Npl4 complex | | 分子名称: | Nuclear protein localization protein 4 homolog, Ubiquitin recognition factor in ER-associated degradation protein 1 | | 著者 | Nguyen, T.Q, Le, L.T.M, Kim, D.H, Ko, K.S, Lee, H.T, Nguyen, Y.T.K, Kim, H.S, Han, B.W, Kang, W, Yang, J.K. | | 登録日 | 2022-02-14 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1.
Structure, 30, 2022
|
|
2IA0
 | | Transcriptional Regulatory Protein PF0864 From Pyrococcus Furiosus a Member of the ASNC Family (PF0864) | | 分子名称: | GOLD ION, Putative HTH-type transcriptional regulator PF0864 | | 著者 | Yang, H, Chang, J, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2006-09-06 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Crystal Structure of the Transcriptional Regulatory Protein PF0864: an Asnc Family member from Pyrococcus Furiosus
To be Published
|
|
7CLT
 | | Crystal structure of the EFhd1/Swiprosin-2, a mitochondrial actin-binding protein | | 分子名称: | CALCIUM ION, EF-hand domain-containing protein D1, GLYCEROL, ... | | 著者 | Mun, S.A, Park, J, Park, K.R, Lee, Y, Kang, J.Y, Park, T, Jin, M, Yang, J, Jun, C.D, Eom, S.H. | | 登録日 | 2020-07-22 | | 公開日 | 2021-01-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.07380986 Å) | | 主引用文献 | Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria.
Front Cell Dev Biol, 8, 2020
|
|
3QYC
 | | Structure of a dimeric anti-HER2 single domain antibody | | 分子名称: | VH domain of IgG molecule | | 著者 | Baral, T.N, Chao, S, Li, S, Tanha, J, Arbabai, M, Wang, S, Zhang, J. | | 登録日 | 2011-03-03 | | 公開日 | 2012-02-08 | | 最終更新日 | 2014-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of a Human Single Domain Antibody Dimer Formed through V(H)-V(H) Non-Covalent Interactions.
Plos One, 7, 2012
|
|
3Q5T
 | |
2PXJ
 | | The complex structure of JMJD2A and monomethylated H3K36 peptide | | 分子名称: | FE (II) ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ... | | 著者 | Chen, Z, Zang, J, Kappler, J, Hong, X, Crawford, F, Zhang, G. | | 登録日 | 2007-05-14 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
3TI5
 | | Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with Zanamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | 著者 | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | | 登録日 | 2011-08-20 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
|
|
2GF7
 | | Double tudor domain structure | | 分子名称: | Jumonji domain-containing protein 2A, SULFATE ION | | 著者 | Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M. | | 登録日 | 2006-03-21 | | 公開日 | 2006-05-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
|
|
3TI6
 | | Crystal structure of 2009 pandemic H1N1 neuraminidase complexed with oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | | 登録日 | 2011-08-20 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
|
|
8IWB
 | | Crystal structure of Q9PR55 at pH 7.5 | | 分子名称: | Uncharacterized protein UU089.1 | | 著者 | Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. | | 登録日 | 2023-03-29 | | 公開日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot.
J.Biol.Chem., 300, 2023
|
|
3TIB
 | | Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir octanoate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-9-O-octanoyl-D-glycero-D-galacto-non-2-enonic acid, CALCIUM ION, ... | | 著者 | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | | 登録日 | 2011-08-20 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
|
|
7JJO
 | | Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor | | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y. | | 登録日 | 2020-07-27 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
|
|
7YAT
 | | CryoEM tetra protofilament structure of the hamster prion 108-144 fibril | | 分子名称: | Major prion protein | | 著者 | Chen, E.H.-L, Kao, S.-W, Lee, C.-H, Huang, J.Y.C, Chen, R.P.-Y, Wu, K.-P. | | 登録日 | 2022-06-28 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | 2.2 angstrom Cryo-EM Tetra-Protofilament Structure of the Hamster Prion 108-144 Fibril Reveals an Ordered Water Channel in the Center.
J.Am.Chem.Soc., 144, 2022
|
|
7Y5X
 | | CryoEM structure of PS2-containing gamma-secretase treated with MRK-560 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | | 登録日 | 2022-06-17 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560.
Nat Commun, 13, 2022
|
|
4XOH
 | | Mechanistic insights into anchorage of the contractile ring from yeast to humans | | 分子名称: | Division mal foutue 1 protein | | 著者 | Chen, Z, Wu, J.-Q, Wang, J, Guan, R, Sun, L, Lee, I.-J, Liu, Y, Chen, M. | | 登録日 | 2015-01-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
|
|
4QNH
 | | Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a | | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | | 著者 | Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F. | | 登録日 | 2014-06-17 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex.
Nat.Chem.Biol., 10, 2014
|
|
7Y5T
 | | CryoEM structure of PS1-containing gamma-secretase in complex with MRK-560 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | | 登録日 | 2022-06-17 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560.
Nat Commun, 13, 2022
|
|
7Y5Z
 | | CryoEM structure of human PS2-containing gamma-secretase | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | | 登録日 | 2022-06-18 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560.
Nat Commun, 13, 2022
|
|
3TIC
 | | Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with zanamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | | 登録日 | 2011-08-20 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
|
|
3TIA
 | | Crystal structure of 1957 pandemic H2N2 neuraminidase complexed with laninamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, ... | | 著者 | Vavricka, C.J, Li, Q, Wu, Y, Qi, J, Wang, M, Liu, Y, Gao, F, Liu, J, Feng, E, He, J, Wang, J, Liu, H, Jiang, H, Gao, G.F. | | 登録日 | 2011-08-20 | | 公開日 | 2011-11-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
|
|
6ILD
 | | Crystal Structure of Human LysRS: P38/AIMP2 Complex II | | 分子名称: | 5'-O-[(S)-hydroxy(methyl)phosphoryl]adenosine, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, ... | | 著者 | Hei, Z, Liu, Z, Wang, J, Fang, P. | | 登録日 | 2018-10-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.882 Å) | | 主引用文献 | Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.
J. Biol. Chem., 294, 2019
|
|
3P5N
 | |
8UXN
 | | Caulobacter crescentus FljM flagellar filament (symmetrized) | | 分子名称: | Flagellin FljM | | 著者 | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | | 登録日 | 2023-11-09 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.11 Å) | | 主引用文献 | Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments
To Be Published
|
|
7XRY
 | | Crystal structure of MERS main protease in complex with inhibitor YH-53 | | 分子名称: | N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, ORF1a | | 著者 | Lin, C, Zhong, F.L, Zhou, X.L, Li, J, Zhang, J. | | 登録日 | 2022-05-12 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor.
Viruses, 14, 2022
|
|
