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PDB: 4145 件
5Y4T
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Crystal structure of Trx domain of Grx3 from Saccharomyces cerevisiae
分子名称: GLYCEROL, Glutaredoxin
著者Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z.
登録日2017-08-05
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J.Mol.Biol., 430, 2018
4WF1
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BU of 4wf1 by Molmil
Crystal structure of the E. coli ribosome bound to negamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C.
登録日2014-09-11
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
8WJL
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Cryo-EM structure of 6-subunit Smc5/6 hinge region
分子名称: E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6
著者Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L.
登録日2023-09-26
公開日2024-06-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (6.15 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
8WJO
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Cryo-EM structure of 8-subunit Smc5/6 arm region
分子名称: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ...
著者Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L.
登録日2023-09-26
公開日2024-06-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (6.04 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
8WJN
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BU of 8wjn by Molmil
Cryo-EM structure of 6-subunit Smc5/6 head region
分子名称: Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosomes element 1, Non-structural maintenance of chromosomes element 4, ...
著者Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L.
登録日2023-09-26
公開日2024-06-26
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.58 Å)
主引用文献Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
6WB8
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Cryo-EM structure of PKD2 C331S disease variant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2
著者Cao, E, Wang, J, Decaen, P.G.
登録日2020-03-26
公開日2020-04-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain.
Proc.Natl.Acad.Sci.USA, 117, 2020
5GJJ
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BU of 5gjj by Molmil
Glutathionylated hHsp70 SBD
分子名称: Heat shock 70 kDa protein 1A
著者Gong, W.B, Yang, J, Zhang, H, Perrett, S.
登録日2016-06-30
公開日2017-07-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of glutathionylated hHsp70 SBD (385-641)
To Be Published
5H3O
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BU of 5h3o by Molmil
Structure of a eukaryotic cyclic nucleotide-gated channel
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION
著者Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J.
登録日2016-10-26
公開日2017-01-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of a eukaryotic cyclic-nucleotide-gated channel.
Nature, 542, 2017
8HNS
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Crystal structure of an anti-CRISPR protein AcrIIC4 in apo form
分子名称: GLYCEROL, anti-CRISPR protein AcrIIC4
著者Sun, W, Cheng, Z, Yang, J, Wang, Y.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
8HNV
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CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4
分子名称: CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ...
著者Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y.
登録日2022-12-08
公開日2023-07-19
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
7YVR
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BU of 7yvr by Molmil
Crystal Structure of L-Threonine Aldolase from Neptunomonas marina
分子名称: GLYCEROL, L-threonine aldolase
著者He, Y.Z, Wang, J, Yan, W.P, Zhang, Y, Feng, Y.
登録日2022-08-19
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery and Engineering of the L-Threonine Aldolase from Neptunomonas marine for the Efficient Synthesis of beta-Hydroxy-alpha-amino Acids via C-C Formation
Acs Catalysis, 2023
6JFK
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BU of 6jfk by Molmil
GDP bound Mitofusin2 (MFN2)
分子名称: CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
3MNM
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BU of 3mnm by Molmil
Crystal structure of GAE domain of GGA2p from Saccharomyces cerevisiae
分子名称: ADP-ribosylation factor-binding protein GGA2, GLYCEROL, SULFATE ION
著者Fang, P, Wang, J, Li, X, Niu, L, Teng, M.
登録日2010-04-21
公開日2010-09-08
最終更新日2014-03-05
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural basis for the specificity of the GAE domain of yGGA2 for its accessory proteins Ent3 and Ent5
Biochemistry, 49, 2010
8A5Y
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BU of 8a5y by Molmil
S. cerevisiae apo unphosphorylated APC/C.
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex and comparison to apo unphosphorylated and phosphorylated states
To Be Published
5V9U
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BU of 5v9u by Molmil
Crystal Structure of small molecule ARS-1620 covalently bound to K-Ras G12C
分子名称: (S)-1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl] piperazin-1-yl}propan-1-one, CALCIUM ION, GLYCEROL, ...
著者Janes, M.R, Zhang, J, Li, L.-S, Hansen, R, Peters, U, Guo, X, Chen, Y, Babbar, A, Firdaus, S.J, Feng, J, Chen, J.H, Li, S, Brehmer, D, Darjania, L, Li, S, Long, Y.O, Thach, C, Liu, Y, Zarieh, A, Ely, T, Kucharski, J.M, Kessler, L.V, Wu, T, Wang, Y, Yao, Y, Deng, X, Zarrinkar, P, Dashyant, D, Lorenzi, M.V, Hu-Lowe, D, Patricelli, M.P, Ren, P, Liu, Y.
登録日2017-03-23
公開日2018-02-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.
Cell, 172, 2018
8XAT
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BU of 8xat by Molmil
Crystal structure of AtARR1(RD-DBD)
分子名称: Two-component response regulator ARR1
著者Li, J.X, Zhou, C.M, Zhang, P, Wang, J.W.
登録日2023-12-05
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献The structure of B-ARR reveals the molecular basis of transcriptional activation by cytokinin.
Proc.Natl.Acad.Sci.USA, 121, 2024
8A61
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S. cerevisiae apo phosphorylated APC/C
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J.
登録日2022-06-16
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C
To Be Published
8A3T
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S. cerevisiae APC/C-Cdh1 complex
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ...
著者Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J.
登録日2022-06-09
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex
To Be Published
5H74
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BU of 5h74 by Molmil
Crystal structure of T2R-TTL-14b complex
分子名称: (2~{S},4~{R})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-3-[hexyl-[(2~{S},3~{S})-3-methyl-2-[[(2~{R})-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-4-methyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-(4-fluorophenyl)-2-methyl-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Wang, Y, Yu, Y, Chen, Q, Yang, J.
登録日2016-11-17
公開日2017-11-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Activity Relationship Studies of Tubulysin Analogues: Anticancer N-Alkyltubulysins with Subpicomolar Activity and the Crystal Structure Binding to Tubulin
To Be Published
6JFL
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BU of 6jfl by Molmil
Nucleotide-free Mitofusin2 (MFN2)
分子名称: CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
5Y4B
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Solution structure of yeast Fra2
分子名称: BolA-like protein 2
著者Tang, Y.J, Chi, C.B, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z.
登録日2017-08-03
公開日2018-03-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J. Mol. Biol., 430, 2018
6JFM
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BU of 6jfm by Molmil
Mitofusin2 (MFN2)_T111D
分子名称: ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
5YZ9
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BU of 5yz9 by Molmil
zinc finger domain of METTL3-METTL14 N6-methyladenosine methyltransferase
分子名称: N6-adenosine-methyltransferase catalytic subunit, ZINC ION
著者Dong, X, Tang, C, Gong, Z, Yin, P, Huang, J.B.
登録日2017-12-13
公開日2018-03-28
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
Protein Cell, 10, 2019
1XMA
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BU of 1xma by Molmil
Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
分子名称: MERCURY (II) ION, Predicted transcriptional regulator, UNKNOWN ATOM OR ION
著者Yang, H, Chen, L, Lee, D, Habel, J, Nguyen, J, Chang, S.-H, Kataeva, I, Xu, H, Chang, J, Zhao, M, Horanyi, P, Florence, Q, Zhou, W, Tempel, W, Lin, D, Praissman, J, Zhang, H, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-10-01
公開日2004-12-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
3K3N
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BU of 3k3n by Molmil
Crystal structure of the catalytic core domain of human PHF8
分子名称: FE (II) ION, PHD finger protein 8
著者Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z.
登録日2009-10-03
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into a novel histone demethylase PHF8
Cell Res., 20, 2010

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