3CQD
 
 | | Structure of the tetrameric inhibited form of phosphofructokinase-2 from Escherichia coli | | 分子名称: | 6-phosphofructokinase isozyme 2, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | 著者 | Ambrosio, A.L, Cabrera, R, Caniuguir, A, Garratt, R.C, Babul, J. | | 登録日 | 2008-04-02 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Crystallographic structure of phosphofructokinase-2 from Escherichia coli in complex with two ATP molecules. Implications for substrate inhibition.
J.Mol.Biol., 383, 2008
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8EC6
 | | Cryo-EM structure of the Glutaminase C core filament (fGAC) | | 分子名称: | Isoform 2 of Glutaminase kidney isoform, mitochondrial, PHOSPHATE ION | | 著者 | Ambrosio, A.L, Dias, S.M, Quesnay, J.E, Portugal, R.V, Cassago, A, van Heel, M.G, Islam, Z, Rodrigues, C.T. | | 登録日 | 2022-09-01 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular mechanism of glutaminase activation through filamentation and the role of filaments in mitophagy protection.
Nat.Struct.Mol.Biol., 30, 2023
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2OM9
 | | Ajulemic acid, a synthetic cannabinoid bound to PPAR gamma | | 分子名称: | (6AR,10AR)-3-(1,1-DIMETHYLHEPTYL)-1-HYDROXY-6,6-DIMETHYL-6A,7,10,10A-TETRAHYDRO-6H-BENZO[C]CHROMENE-9-CARBOXYLIC ACID, Peroxisome proliferator-activated receptor gamma | | 著者 | Ambrosio, A.L.B, Garratt, R.C. | | 登録日 | 2007-01-21 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Ajulemic Acid, a Synthetic Nonpsychoactive Cannabinoid Acid, Bound to the Ligand Binding Domain of the Human Peroxisome Proliferator-activated Receptor gamma
J.Biol.Chem., 282, 2007
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3SS3
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3SS5
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3SS4
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1S8H
 | | Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, first fatty acid free form | | 分子名称: | Phospholipase A2 homolog, SULFATE ION | | 著者 | Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C. | | 登録日 | 2004-02-02 | | 公開日 | 2004-02-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
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1S8G
 | | Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form | | 分子名称: | GLYCEROL, LAURIC ACID, Phospholipase A2 homolog, ... | | 著者 | Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C. | | 登録日 | 2004-02-02 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
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1S8I
 | | Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, second fatty acid free form | | 分子名称: | Phospholipase A2 homolog, SULFATE ION | | 著者 | Ambrosio, A.L.B, de Souza, D.H.F, Nonato, M.C, Selistre de Araujo, H.S, Ownby, C.L, Garratt, R.C. | | 登録日 | 2004-02-02 | | 公開日 | 2004-02-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.609 Å) | | 主引用文献 | A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
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4WN5
 | | Crystal structure of the C-terminal Per-Arnt-Sim (PASb) of human HIF-3alpha9 bound to 18:1-1-monoacylglycerol | | 分子名称: | HEXAETHYLENE GLYCOL, Hypoxia-inducible factor 3-alpha, MONOVACCENIN, ... | | 著者 | Fala, A.M, Oliveira, J.F, Dias, S.M, Ambrosio, A.L. | | 登録日 | 2014-10-10 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3 alpha.
Sci Rep, 5, 2015
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5F28
 | | Crystal structure of FAT domain of Focal Adhesion Kinase (FAK) bound to the transcription factor MEF2C | | 分子名称: | Focal adhesion kinase 1, MEF2C | | 著者 | Cardoso, A.C, Ambrosio, A.L.B, Dessen, A, Franchini, K.G. | | 登録日 | 2015-12-01 | | 公開日 | 2016-07-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes.
Structure, 24, 2016
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8TNV
 | | Hemocyanin Functional Unit CCHB-g of Concholepas concholepas | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Munoz, S, Vallejos-Baccelliere, G, Manubens, A, Salazar, M, Nascimento, A.F.Z, Ambrosio, A.L.B, Becker, M.I, Guixe, V, Castro-Fernandez, V. | | 登録日 | 2023-08-02 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into a functional unit from an immunogenic mollusk hemocyanin.
Structure, 32, 2024
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4JJM
 | | Structure of a cyclophilin from Citrus sinensis (CsCyp) in complex with cyclosporin A | | 分子名称: | Peptidyl-prolyl cis-trans isomerase, cyclosporin A | | 著者 | Campos, B.M, Ambrosio, A.L.B, Souza, T.A.C.B, Barbosa, J.A.R.G, Benedetti, C.E. | | 登録日 | 2013-03-08 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | A redox 2-cys mechanism regulates the catalytic activity of divergent cyclophilins.
Plant Physiol., 162, 2013
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4JKT
 | | Crystal structure of mouse Glutaminase C, BPTES-bound form | | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | | 著者 | Fornezari, C, Ferreira, A.P.S, Dias, S.M.G, Ambrosio, A.L.B. | | 登録日 | 2013-03-11 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
J.Biol.Chem., 288, 2013
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4BQM
 | | Crystal structure of human liver-type glutaminase, catalytic domain | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLUTAMINASE LIVER ISOFORM, ... | | 著者 | Ferreira, I.M, Vollmar, M, Krojer, T, Strain-Damerell, C, Froese, S, Coutandin, D, Williams, E, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Dias, S.M.G, Ambrosio, A.L.B, Yue, W.W. | | 登録日 | 2013-05-31 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain
To be Published
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5U0K
 | | C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA) | | 分子名称: | Glutaminase liver isoform, mitochondrial | | 著者 | Ferreira, I.M, Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B. | | 登録日 | 2016-11-24 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.548 Å) | | 主引用文献 | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
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5U0I
 | | C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - tetragonal crystal form | | 分子名称: | CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ... | | 著者 | Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B. | | 登録日 | 2016-11-24 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.423 Å) | | 主引用文献 | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
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5U0J
 | | C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - monoclinic crystal form | | 分子名称: | Glutaminase kidney isoform, mitochondrial, SODIUM ION | | 著者 | Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B. | | 登録日 | 2016-11-24 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
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5UQE
 | | Multidomain structure of human kidney-type glutaminase(KGA/GLS) | | 分子名称: | Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | | 著者 | Pasquali, C.C, Dias, S.M.G, Ambrosio, A.L.B. | | 登録日 | 2017-02-08 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
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3FEY
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3FEX
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2B4J
 | | Structural basis for the recognition between HIV-1 integrase and LEDGF/p75 | | 分子名称: | GLYCEROL, Integrase (IN), PC4 and SFRS1 interacting protein, ... | | 著者 | Cherepanov, P, Ambrosio, A.L, Rahman, S, Ellenberger, T, Engelman, A. | | 登録日 | 2005-09-24 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2H77
 | | Crystal structure of human TR alpha bound T3 in monoclinic space group | | 分子名称: | 3,5,3'TRIIODOTHYRONINE, THRA protein | | 著者 | Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I. | | 登録日 | 2006-06-01 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
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2H79
 | | Crystal Structure of human TR alpha bound T3 in orthorhombic space group | | 分子名称: | 3,5,3'TRIIODOTHYRONINE, THRA protein | | 著者 | Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I. | | 登録日 | 2006-06-01 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
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3SUJ
 | | Crystal structure of cerato-platanin 1 from M. perniciosa (MpCP1) | | 分子名称: | ACETATE ION, CHLORIDE ION, Cerato-platanin 1, ... | | 著者 | Oliveira, J.F, Barsottini, M.R.O, Zaparoli, G, Machado, L.O, Dias, S.M.G, Pereira, G.A.G, Ambrosio, A.L.B. | | 登録日 | 2011-07-11 | | 公開日 | 2012-07-11 | | 最終更新日 | 2019-02-06 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
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