5UQE

Multidomain structure of human kidney-type glutaminase(KGA/GLS)

Summary for 5UQE

• Entry DOI: 10.2210/pdb5uqe/pdb
• Descriptor: Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) (2 entities in total)
• Functional Keywords: glutaminase, human, kidney-type, kga, gls, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 5
• Total formula weight: 292296.13

Authors

Pasquali, C.C.,Dias, S.M.G.,Ambrosio, A.L.B. (deposition date: 2017-02-08, release date: 2017-05-24, Last modification date: 2024-03-06)

• Primary citation: Pasquali, C.C.,Islam, Z.,Adamoski, D.,Ferreira, I.M.,Righeto, R.D.,Bettini, J.,Portugal, R.V.,Yue, W.W.,Gonzalez, A.,Dias, S.M.G.,Ambrosio, A.L.B.; The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.; J. Biol. Chem., 292:11572-11585, 2017; PubMed: 28526749; DOI: 10.1074/jbc.M117.787291

Experimental method

X-RAY DIFFRACTION (3.6 Å)