1S8G

Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form

Summary for 1S8G

Related1S8H 1S8I
DescriptorPhospholipase A2 homolog, SULFATE ION, LAURIC ACID, ... (5 entities in total)
Functional Keywordslys49-phospholipase a2, snake venom, myotoxicity, fatty acid bound form, hydrolase, toxin
Biological sourceAgkistrodon contortrix laticinctus (broad-banded copperhead)
Cellular locationSecreted P49121
Total number of polymer chains1
Total molecular weight14437.87
Authors
Ambrosio, A.L.B.,de Souza, D.H.F.,Nonato, M.C.,Selistre de Araujo, H.S.,Ownby, C.L.,Garratt, R.C. (deposition date: 2004-02-02, release date: 2004-02-10, Last modification date: 2011-07-13)
Primary citation
Ambrosio, A.L.B.,Nonato, M.C.,Selistre de Araujo, H.S.,Arni, R.,Ward, R.J.,Ownby, C.L.,de Souza, D.H.F.,Garratt, R.C.
A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280:7326-7335, 2005
PubMed: 15596433 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M410588200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24620 3.7% 8.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169117
PDB entries from 2020-09-23