Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1S8G

Crystal structure of Lys49-Phospholipase A2 from Agkistrodon contortrix laticinctus, fatty acid bound form

Functional Information from GO Data
ChainGOidnamespacecontents
A0004623molecular_functionphospholipase A2 activity
A0005509molecular_functioncalcium ion binding
A0005543molecular_functionphospholipid binding
A0005576cellular_componentextracellular region
A0006644biological_processphospholipid metabolic process
A0008201molecular_functionheparin binding
A0016042biological_processlipid catabolic process
A0035821biological_processmodulation of process of another organism
A0042130biological_processnegative regulation of T cell proliferation
A0047498molecular_functioncalcium-dependent phospholipase A2 activity
A0050482biological_processarachidonate secretion
A0090729molecular_functiontoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 134
ChainResidue
AHIS33
AARG34
ALYS53

site_idAC2
Number of Residues11
DetailsBINDING SITE FOR RESIDUE DAO A 135
ChainResidue
AGLY30
ACYS45
AVAL102
APHE124
AGOL136
ALEU2
ALEU3
AGLY6
AILE9
AALA18
ATYR22

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL A 136
ChainResidue
ALEU5
AGLY30
AHIS48
ATYR52
ADAO135
AHOH266

Functional Information from PROSITE/UniProt
site_idPS00118
Number of Residues8
DetailsPA2_HIS Phospholipase A2 histidine active site. CCFvHKcC
ChainResidueDetails
ACYS44-CYS51

site_idPS00119
Number of Residues11
DetailsPA2_ASP Phospholipase A2 aspartic acid active site. MCECDKAVaIC
ChainResidueDetails
AMET95-CYS105

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1n29
ChainResidueDetails
AHIS48
AGLY30
AASP99

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon