5F28
Crystal structure of FAT domain of Focal Adhesion Kinase (FAK) bound to the transcription factor MEF2C
Summary for 5F28
| Entry DOI | 10.2210/pdb5f28/pdb |
| Descriptor | MEF2C, Focal adhesion kinase 1 (3 entities in total) |
| Functional Keywords | transcription factor, kinase, cardiovascular disease, transcription, protein binding |
| Biological source | Mus musculus (mouse) More |
| Total number of polymer chains | 7 |
| Total formula weight | 94405.41 |
| Authors | Cardoso, A.C.,Ambrosio, A.L.B.,Dessen, A.,Franchini, K.G. (deposition date: 2015-12-01, release date: 2016-07-13, Last modification date: 2023-09-27) |
| Primary citation | Cardoso, A.C.,Pereira, A.H.M.,Ambrosio, A.L.B.,Consonni, S.R.,Rocha de Oliveira, R.,Bajgelman, M.C.,Dias, S.M.G.,Franchini, K.G. FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes. Structure, 24:1301-1310, 2016 Cited by PubMed: 27427476DOI: 10.1016/j.str.2016.06.003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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