3SS3

Crystal structure of mouse Glutaminase C, ligand-free form

Summary for 3SS3

Related3SS4 3SS5
DescriptorGlutaminase C, CHLORIDE ION (3 entities in total)
Functional Keywordsglutaminase, l-glutamine, mitochondria, hydrolase
Biological sourceMus musculus (mouse)
Total number of polymer chains4
Total molecular weight213449.66
Authors
Ambrosio, A.L.B.,Dias, S.M.G.,Cerione, R.A. (deposition date: 2011-07-07, release date: 2012-01-11, Last modification date: 2012-04-04)
Primary citation
Cassago, A.,Ferreira, A.P.,Ferreira, I.M.,Fornezari, C.,Gomes, E.R.,Greene, K.S.,Pereira, H.M.,Garratt, R.C.,Dias, S.M.,Ambrosio, A.L.
Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109:1092-1097, 2012
PubMed: 22228304 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1112495109
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.42 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.240110.1%5.5%2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3ss3
no rotation
Molmil generated image of 3ss3
rotated about x axis by 90°
Molmil generated image of 3ss3
rotated about y axis by 90°