2IW3
 
 | | Elongation Factor 3 in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ELONGATION FACTOR 3A, SULFATE ION | | Authors: | Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R. | | Deposit date: | 2006-06-26 | | Release date: | 2006-08-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
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4CXG
 | | Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | | Descriptor: | 18S RRNA - H44, 18S RRNA - H5-H14, 18S RRNA - H8, ... | | Authors: | Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T. | | Deposit date: | 2014-04-07 | | Release date: | 2014-07-16 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
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4CXH
 | | Regulation of the mammalian elongation cycle by 40S subunit rolling: a eukaryotic-specific ribosome rearrangement | | Descriptor: | 18S RRNA - H44, 18S RRNA - H5-H14, 18S RRNA - H8, ... | | Authors: | Budkevich, T.V, Giesebrecht, J, Behrmann, E, Loerke, J, Ramrath, D.J.F, Mielke, T, Ismer, J, Hildebrand, P, Tung, C.-S, Nierhaus, K.H, Sanbonmatsu, K.Y, Spahn, C.M.T. | | Deposit date: | 2014-04-07 | | Release date: | 2014-07-16 | | Last modified: | 2019-06-26 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
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2ZJR
 | | Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans | | Descriptor: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Harms, J.M, Wilson, D.N, Schluenzen, F, Connell, S.R, Stachelhaus, T, Zaborowska, Z, Spahn, C.M.T, Fucini, P. | | Deposit date: | 2008-03-08 | | Release date: | 2008-06-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
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1TRJ
 | | Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome | | Descriptor: | Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA | | Authors: | Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J. | | Deposit date: | 2004-06-21 | | Release date: | 2004-09-28 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (11.7 Å) | | Cite: | Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
Nat.Struct.Mol.Biol., 11, 2004
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4D61
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-07 | | Release date: | 2015-03-04 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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4D67
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | 28S RRNA, 5.8S RRNA, 5S RRNA, ... | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-10 | | Release date: | 2015-03-04 | | Last modified: | 2019-10-23 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
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4D5L
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-05 | | Release date: | 2015-02-04 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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4D5Y
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ... | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-07 | | Release date: | 2015-03-04 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
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3DEG
 | | Complex of elongating Escherichia coli 70S ribosome and EF4(LepA)-GMPPNP | | Descriptor: | 30S RNA helix 14, 30S RNA helix 8, 30S ribosomal protein S12, ... | | Authors: | Connell, S.R, Topf, M, Qin, Y, Wilson, D.N, Mielke, T, Fucini, P, Nierhaus, K.H, Spahn, C.M.T. | | Deposit date: | 2008-06-10 | | Release date: | 2008-08-19 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (10.9 Å) | | Cite: | A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
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2NOQ
 | | Structure of ribosome-bound cricket paralysis virus IRES RNA | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S5, ... | | Authors: | Schuler, M, Connell, S.R, Lescoute, A, Giesebrecht, J, Dabrowski, M, Schroeer, B, Mielke, T, Penczek, P.A, Westhof, E, Spahn, C.M.T. | | Deposit date: | 2006-10-26 | | Release date: | 2006-11-21 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (7.3 Å) | | Cite: | Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Nat.Struct.Mol.Biol., 13, 2006
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4D5N
 | | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | | Descriptor: | CRICKET PARALYSIS VIRUS IRES RNA, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 | | Authors: | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | | Deposit date: | 2014-11-06 | | Release date: | 2015-02-04 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
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1EG0
 | | FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME | | Descriptor: | FORMYL-METHIONYL-TRNA, FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, ... | | Authors: | Gabashvili, I.S, Agrawal, R.K, Spahn, C.M.T, Grassucci, R.A, Svergun, D.I, Frank, J, Penczek, P. | | Deposit date: | 2000-02-11 | | Release date: | 2000-03-06 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (11.5 Å) | | Cite: | Solution structure of the E. coli 70S ribosome at 11.5 A resolution.
Cell(Cambridge,Mass.), 100, 2000
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1P75
 | | Crystal structure of EHV4-TK complexed with TP5A | | Descriptor: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, Thymidine kinase | | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2003-04-30 | | Release date: | 2003-11-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Structure, 11, 2003
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1RY1
 | | Structure of the signal recognition particle interacting with the elongation-arrested ribosome | | Descriptor: | SRP Alu domain, SRP RNA, SRP S domain, ... | | Authors: | Halic, M, Becker, T, Pool, M.R, Spahn, C.M, Grassucci, R.A, Frank, J, Beckmann, R. | | Deposit date: | 2003-12-19 | | Release date: | 2004-04-20 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Structure of the signal recognition particle interacting with the elongation-arrested ribosome
Nature, 427, 2004
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1P73
 | | Crystal structure of EHV4-TK complexed with TP4A | | Descriptor: | P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, SULFATE ION, Thymidine kinase | | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2003-04-30 | | Release date: | 2003-11-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Structure, 11, 2003
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2ORW
 | | Thermotoga maritima thymidine kinase 1 like enzyme in complex with TP4A | | Descriptor: | MAGNESIUM ION, P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, Thymidine kinase, ... | | Authors: | Segura-Pena, D, Lutz, S, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2007-02-04 | | Release date: | 2007-03-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure.
J.Mol.Biol., 369, 2007
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1AXM
 | | HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR | | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR | | Authors: | DiGabriele, A.D, Lax, I, Chen, D.I, Svahn, C.M, Jaye, M, Schlessinger, J, Hendrickson, W.A. | | Deposit date: | 1997-10-16 | | Release date: | 1998-04-22 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of a heparin-linked biologically active dimer of fibroblast growth factor.
Nature, 393, 1998
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3RGW
 | | Crystal structure at 1.5 A resolution of an H2-reduced, O2-tolerant hydrogenase from Ralstonia eutropha unmasks a novel iron-sulfur cluster | | Descriptor: | FE3-S4 CLUSTER, FE4-S3 CLUSTER, IRON/SULFUR CLUSTER, ... | | Authors: | Scheerer, P, Fritsch, J, Frielingsdorf, S, Kroschinsky, S, Friedrich, B, Lenz, O, Spahn, C.M.T. | | Deposit date: | 2011-04-10 | | Release date: | 2011-10-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre.
Nature, 479, 2011
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1T1M
 | | Binding position of ribosome recycling factor (RRF) on the E. coli 70S ribosome | | Descriptor: | 42-mer fragment of double helix from 16S rRNA, dodecamer fragment of double helix from 23S rRNA, ribosome recycling factor | | Authors: | Agrawal, R.K, Sharma, M.R, Kiel, M.C, Hirokawa, G, Booth, T.M, Spahn, C.M, Grassucci, R.A, Kaji, A, Frank, J. | | Deposit date: | 2004-04-16 | | Release date: | 2004-06-15 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
Proc.Natl.Acad.Sci.USA, 101, 2004
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1P72
 | | Crystal structure of EHV4-TK complexed with Thy and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, THYMIDINE, ... | | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2003-04-30 | | Release date: | 2003-11-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Structure, 11, 2003
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2ORV
 | | human Thymidine Kinase 1 in complex with TP4A | | Descriptor: | P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, Thymidine kinase, ZINC ION | | Authors: | Segura-Pena, D, Lutz, S, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2007-02-04 | | Release date: | 2007-03-27 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure.
J.Mol.Biol., 369, 2007
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1P60
 | | Structure of human dCK complexed with 2'-Deoxycytidine and ADP, Space group C 2 2 21 | | Descriptor: | 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase | | Authors: | Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2003-04-28 | | Release date: | 2003-07-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
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1P6X
 | | Crystal structure of EHV4-TK complexed with Thy and SO4 | | Descriptor: | SULFATE ION, THYMIDINE, Thymidine kinase | | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2003-04-30 | | Release date: | 2003-11-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Structure, 11, 2003
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1P7C
 | | Crystal Structure of HSV1-TK complexed with TP5A | | Descriptor: | P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, THYMIDINE, ... | | Authors: | Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. | | Deposit date: | 2003-05-01 | | Release date: | 2003-11-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases.
Structure, 11, 2003
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