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2ORV

human Thymidine Kinase 1 in complex with TP4A

Summary for 2ORV
Entry DOI10.2210/pdb2orv/pdb
Related2ORW
DescriptorThymidine kinase, ZINC ION, P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, ... (4 entities in total)
Functional Keywordstk-1 (thymidine kinase 1), tp4a (p1-(5'-adenosyl)p4-(5'-(2'deoxythymidil))tetraphosphate, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P04183
Total number of polymer chains2
Total formula weight52512.66
Authors
Segura-Pena, D.,Lutz, S.,Monnerjahn, C.,Konrad, M.,Lavie, A. (deposition date: 2007-02-04, release date: 2007-03-27, Last modification date: 2024-02-21)
Primary citationSegura-Pena, D.,Lutz, S.,Monnerjahn, C.,Konrad, M.,Lavie, A.
Binding of ATP to TK1-like Enzymes Is Associated with a Conformational Change in the Quaternary Structure.
J.Mol.Biol., 369:129-141, 2007
Cited by
PubMed: 17407781
DOI: 10.1016/j.jmb.2007.02.104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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