2ORV
human Thymidine Kinase 1 in complex with TP4A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidine kinase | polymer | 234 | 25383.6 | 2 | UniProt (P04183) Pfam (PF00265) | Homo sapiens (human) | |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE | non-polymer | 807.3 | 2 | Chemie (4TA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 234 (UniProt: P04183)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Lys 203 | engineered mutation |
| Ala 204 | Glu 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50767.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1745.5 | |
| All* | Total formula weight | 52512.7 |
