4D61

Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state

Summary for 4D61

EMDB information2813
Descriptor18S RRNA, 40S RIBOSOMAL PROTEIN SA, 40S RIBOSOMAL PROTEIN S3A, ... (37 entities in total)
Functional Keywordscrpv ires, ribosome, termination, release factors
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationCytoplasm P62495
Total number of polymer chains37
Total molecular weight1383135.66
Authors
Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T. (deposition date: 2014-11-07, release date: 2015-03-04, Last modification date: 2017-08-30)
Primary citation
Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T.
Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57:422-, 2015
PubMed: 25601755 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2014.12.016
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (9 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone402.7%4.3%0.24MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report