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5YJ5
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BU of 5yj5 by Molmil
structure for wildtype Human prion protein (M129)
分子名称: Major prion protein
著者Zheng, Z, Lin, D.
登録日2017-10-08
公開日2018-04-11
最終更新日2019-04-24
実験手法SOLUTION NMR
主引用文献Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease.
Sci Rep, 8, 2018
5YJ4
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BU of 5yj4 by Molmil
structure for the protective mutant G127V of Human prion protein
分子名称: Major prion protein
著者Zheng, Z, Lin, D.
登録日2017-10-07
公開日2018-04-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease.
Sci Rep, 8, 2018
8HFQ
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BU of 8hfq by Molmil
Cryo-EM structure of CpcL-PBS from cyanobacterium Synechocystis sp. PCC 6803
分子名称: C-phycocyanin alpha subunit, C-phycocyanin beta subunit, Ferredoxin--NADP reductase, ...
著者Zheng, L, Zhang, Z, Wang, H, Zheng, Z, Gao, N, Zhao, J.
登録日2022-11-11
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Cryo-EM and femtosecond spectroscopic studies provide mechanistic insight into the energy transfer in CpcL-phycobilisomes.
Nat Commun, 14, 2023
8IX3
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BU of 8ix3 by Molmil
Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement)
分子名称: BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11
著者Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S.
登録日2023-03-31
公開日2023-11-15
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.
J.Virol., 97, 2023
7EXT
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BU of 7ext by Molmil
Cryo-EM structure of cyanobacterial phycobilisome from Synechococcus sp. PCC 7002
分子名称: Allophycocyanin alpha subunit, Allophycocyanin beta subunit, Allophycocyanin subunit alpha-B, ...
著者Zheng, L, Zheng, Z, Li, X, Wang, G, Zhang, K, Wei, P, Zhao, J, Gao, N.
登録日2021-05-28
公開日2021-10-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes.
Nat Commun, 12, 2021
7EYD
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BU of 7eyd by Molmil
Cryo-EM structure of cyanobacterial phycobilisome from Anabaena sp. PCC 7120
分子名称: Allophycocyanin subunit alpha 1, Allophycocyanin subunit alpha-B, Allophycocyanin subunit beta, ...
著者Zheng, L, Zheng, Z, Li, X, Wang, G, Zhang, K, Wei, P, Zhao, J, Gao, N.
登録日2021-05-30
公開日2021-10-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes.
Nat Commun, 12, 2021
4ZWJ
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BU of 4zwj by Molmil
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
分子名称: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
著者Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR)
登録日2015-05-19
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
4JHA
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BU of 4jha by Molmil
Crystal Structure of RSV-Neutralizing Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-04
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4JHW
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BU of 4jhw by Molmil
Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-05
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
2QZ7
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BU of 2qz7 by Molmil
The crystal structure of a homologue of telluride resistance protein (TerD), SCO6318 from Streptomyces coelicolor A3(2)
分子名称: 1,2-ETHANEDIOL, SODIUM ION, Uncharacterized protein SCO6318
著者Tan, K, Xu, X, Zheng, Z, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-08-16
公開日2007-08-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of a homologue of telluride resistance protein (TerD), SCO6318 from Streptomyces coelicolor A3(2).
To be Published
4JYP
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BU of 4jyp by Molmil
crystal Structure of KAI2 Apo form
分子名称: Hydrolase, alpha/beta fold family protein
著者Guo, Y, Zheng, Z, Noel, J.P.
登録日2013-03-31
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JYM
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crystal Structure of KAI2 in complex with 3-methyl-2H-furo[2,3-c]pyran-2-one
分子名称: 3-methyl-2H-furo[2,3-c]pyran-2-one, Hydrolase, alpha/beta fold family protein
著者Guo, Y, Zheng, Z, Noel, J.P.
登録日2013-03-30
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Smoke-derived karrikin perception by the alpha/beta-hydrolase KAI2 from Arabidopsis.
Proc.Natl.Acad.Sci.USA, 110, 2013
7WHZ
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BU of 7whz by Molmil
SARS-CoV-2 spike protein in complex with three human neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ...
著者Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S.
登録日2022-01-01
公開日2022-06-22
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
7WI0
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BU of 7wi0 by Molmil
SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ...
著者Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S.
登録日2022-01-01
公開日2022-06-22
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
6JV4
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BU of 6jv4 by Molmil
Crystal structure of metallo-beta-lactamase VMB-1
分子名称: CITRIC ACID, VMB-1, ZINC ION
著者Cheng, Q, Chen, S.
登録日2019-04-15
公開日2019-11-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Genetic and Biochemical Characterization of VMB-1, a Novel Metallo-beta-Lactamase Encoded by a Conjugative, Broad-Host Range IncC Plasmid from Vibrio spp.
Adv Biosyst, 4, 2020
3RO3
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BU of 3ro3 by Molmil
crystal structure of LGN/mInscuteable complex
分子名称: CHLORIDE ION, ETHANOL, G-protein-signaling modulator 2, ...
著者Zhu, J, Wen, W, Shang, Y, Wei, Z, Pan, Z, Wang, W, Zhang, M.
登録日2011-04-25
公開日2012-03-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
3RO2
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BU of 3ro2 by Molmil
Structures of the LGN/NuMA complex
分子名称: G-protein-signaling modulator 2, GLYCEROL, peptide of Nuclear mitotic apparatus protein 1
著者Shang, Y, Wei, Z.
登録日2011-04-25
公開日2012-03-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
6LAT
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BU of 6lat by Molmil
The cryo-EM structure of HEV VLP
分子名称: Protein ORF2
著者Zheng, Q, He, M, Li, S.
登録日2019-11-13
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Viral neutralization by antibody-imposed physical disruption.
Proc.Natl.Acad.Sci.USA, 2019
6LB0
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BU of 6lb0 by Molmil
The cryo-EM structure of HEV VLP in complex with Fab 8C11
分子名称: Protein ORF2
著者Zheng, Q, He, M, Li, S.
登録日2019-11-13
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Viral neutralization by antibody-imposed physical disruption.
Proc.Natl.Acad.Sci.USA, 2019
6PKA
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BU of 6pka by Molmil
Structure of ClpP from Staphylococcus aureus in complex with ureadepsipeptide
分子名称: ATP-dependent Clp protease proteolytic subunit, OO1-WFP-SER-PRO-YCP-ALA-MP8 ureadepsipeptide
著者Griffith, E.C, Lee, R.E.
登録日2019-06-28
公開日2019-11-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Ureadepsipeptides as ClpP Activators.
Acs Infect Dis., 5, 2019
6PRT
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BU of 6prt by Molmil
Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 10 (methyl [(3R)-1-methyl-5-oxopyrrolidin-3-yl]acetate)
分子名称: Bromodomain-containing protein 4, methyl [(3R)-1-methyl-5-oxopyrrolidin-3-yl]acetate
著者Ilyichova, O.V, Scanlon, M.J.
登録日2019-07-11
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.
Bioorg.Med.Chem., 27, 2019
6PMD
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BU of 6pmd by Molmil
Structure of ClpP from Staphylococcus aureus in complex with Acyldepsipeptide
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit, SHV-WFP-SER-PRO-YCP-ALA-MP8 Acyldepsipeptide
著者Griffith, E.C, Lee, R.E.
登録日2019-07-01
公開日2019-11-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Ureadepsipeptides as ClpP Activators.
Acs Infect Dis., 5, 2019
6PS9
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Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 17 (5-{2-[(3R)-1-methyl-5-oxopyrrolidin-3-yl]ethyl}-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one)
分子名称: 5-{2-[(3R)-1-methyl-5-oxopyrrolidin-3-yl]ethyl}-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one, Bromodomain-containing protein 4
著者Ilyichova, O.V, Scanlon, M.J.
登録日2019-07-12
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.
Bioorg.Med.Chem., 27, 2019
6PSB
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BU of 6psb by Molmil
Crystal structure of BRD4 bromodomain 1 with N-methylpyrrolidin-2-one (NMP) derivative 18 (5-{[(3R)-1-methyl-5-oxopyrrolidin-3-yl]methyl}-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one)
分子名称: 5-{[(3R)-1-methyl-5-oxopyrrolidin-3-yl]methyl}-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one, Bromodomain-containing protein 4
著者Ilyichova, O.V, Scanlon, M.J.
登録日2019-07-12
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.
Bioorg.Med.Chem., 27, 2019
6CLV
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BU of 6clv by Molmil
Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure
分子名称: 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide, Dihydropteroate synthase
著者Gajewski, S, Griffith, E.C, Wu, Y, White, S.W.
登録日2018-03-02
公開日2018-08-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase.
Front Microbiol, 9, 2018

 

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