5G05
| Cryo-EM structure of combined apo phosphorylated APC | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | Authors: | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | Deposit date: | 2016-03-16 | Release date: | 2016-05-25 | Last modified: | 2019-09-11 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation. Nature, 533, 2016
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5G04
| Structure of the human APC-Cdc20-Hsl1 complex | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | Authors: | Zhang, S, Chang, L, Alfieri, C, Zhang, Z, Yang, J, Maslen, S, Skehel, M, Barford, D. | Deposit date: | 2016-03-16 | Release date: | 2016-05-25 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular Mechanism of Apc/C Activation by Mitotic Phosphorylation. Nature, 533, 2016
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2MSU
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8OW1
| Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | Descriptor: | C0N3, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | Authors: | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D. | Deposit date: | 2023-04-26 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9, 2023
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8OVW
| Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA | Descriptor: | C0N3 DNA, Centromere-binding protein 1, Inner kinetochore subunit AME1, ... | Authors: | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D. | Deposit date: | 2023-04-26 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9, 2023
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8OVX
| Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus | Descriptor: | Inner kinetochore subunit AME1, Inner kinetochore subunit CTF19, Inner kinetochore subunit MCM21, ... | Authors: | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S. | Deposit date: | 2023-04-26 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9, 2023
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8OW0
| Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome | Descriptor: | C0N3 DNA, Centromere-binding protein 1, Histone H2A.1, ... | Authors: | Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D. | Deposit date: | 2023-04-26 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9, 2023
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8JDG
| Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid | Descriptor: | (2R)-2-oxidanylbutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-14 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDB
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid | Descriptor: | (2R)-2-oxidanyloctanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDR
| Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid | Descriptor: | (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDN
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid | Descriptor: | (2R)-2-oxidanylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDQ
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid | Descriptor: | (2R)-2-hydroxy-4-methylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDC
| Crystal structure of mLDHD in apo form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.696 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDO
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid | Descriptor: | (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDT
| Crystal structure of mLDHD in complex with 2-ketobutanoic acid | Descriptor: | 2-KETOBUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDU
| Crystal structure of mLDHD in complex with 2-ketovaleric acid | Descriptor: | 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDX
| Crystal structure of mLDHD in complex with 2-ketoisovaleric acid | Descriptor: | 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDD
| Crystal structure of H405A mLDHD in apo form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDF
| Crystal structure of H405A mLDHD in complex with D-lactate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDS
| Crystal structure of mLDHD in complex with Pyruvate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, PYRUVIC ACID, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.636 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDE
| Crystal structure of mLDHD in complex with D-lactate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-13 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.729 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDP
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid | Descriptor: | DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDV
| Crystal structure of mLDHD in complex with 2-ketohexanoic acid | Descriptor: | 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDY
| Crystal structure of mLDHD in complex with 2-ketoisocaproic acid | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDZ
| Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid | Descriptor: | (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | Authors: | Jin, S, Chen, X, Yang, J, Ding, J. | Deposit date: | 2023-05-15 | Release date: | 2023-10-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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