8OW0

Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome

Summary for 8OW0

Entry DOI	10.2210/pdb8ow0/pdb
EMDB information	17226
Descriptor	C0N3 DNA, Inner kinetochore subunit MCM22, Inner kinetochore subunit IML3, ... (20 entities in total)
Functional Keywords	kinetochore, point centromere, cenp-a nucleosome, topological entrapment, centromeric dna, cell cycle
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	25
Total formula weight	787725.54
Authors	Dendooven, T.D.,Zhang, Z.,Yang, J.,McLaughlin, S.,Schwabb, J.,Scheres, S.,Yatskevich, S.,Barford, D. (deposition date: 2023-04-26, release date: 2023-08-09)
Primary citation	Dendooven, T.,Zhang, Z.,Yang, J.,McLaughlin, S.H.,Schwab, J.,Scheres, S.H.W.,Yatskevich, S.,Barford, D. Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9:eadg7480-eadg7480, 2023 Cited by PubMed: 37506202 DOI: 10.1126/sciadv.adg7480 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation