4J8R
 
 | | Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment | | Descriptor: | Heavy chain of POM2 Fab, Light chain of POM2 Fab, Major prion protein | | Authors: | Swayampakula, M, Baral, P.K, Kav, N.N.V, Aguzzi, A, James, M.N.G. | | Deposit date: | 2013-02-14 | | Release date: | 2013-05-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.
Protein Sci., 22, 2013
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8ARH
 | | In situ subtomogram average of Vaccinia virus (WR) D13 lattice, on immature virions | | Descriptor: | Scaffold protein D13 | | Authors: | Calcraft, T, Hernandez-Gonzalez, M, Nans, A, Rosenthal, P.B, Way, M. | | Deposit date: | 2022-08-16 | | Release date: | 2023-02-01 | | Last modified: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (19.200001 Å) | | Cite: | A succession of two viral lattices drives vaccinia virus assembly.
Plos Biol., 21, 2023
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8R5I
 | | In situ structure of the Vaccinia virus (WR) A4/A10 palisade trimer in mature virions by flexible fitting into a cryoET map | | Descriptor: | Core protein A10, Core protein A4 | | Authors: | Calcraft, T, Hernandez-Gonzalez, M, Nans, A, Rosenthal, P.B, Way, M. | | Deposit date: | 2023-11-16 | | Release date: | 2024-01-10 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (9.7 Å) | | Cite: | Palisade structure in intact vaccinia virions.
Mbio, 15, 2024
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6EJN
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3J82
 | | Electron cryo-microscopy of DNGR-1 in complex with F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Hanc, P, Fujii, T, Yamada, Y, Huotari, J, Schulz, O, Ahrens, S, Kjaer, S, Way, M, Namba, K, Reis e Sousa, C. | | Deposit date: | 2014-09-25 | | Release date: | 2015-05-20 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Structure of the Complex of F-Actin and DNGR-1, a C-Type Lectin Receptor Involved in Dendritic Cell Cross-Presentation of Dead Cell-Associated Antigens.
Immunity, 42, 2015
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1PRQ
 | | ACANTHAMOEBA CASTELLANII PROFILIN IA | | Descriptor: | PROFILIN IA | | Authors: | Fedorov, A.A, Pollard, T.D, Way, M, Lattman, E.E, Almo, S.C. | | Deposit date: | 1997-08-18 | | Release date: | 1997-12-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii.
J.Struct.Biol., 123, 1998
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4DGI
 | | Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230 | | Descriptor: | Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ... | | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | | Deposit date: | 2012-01-26 | | Release date: | 2012-10-31 | | Last modified: | 2013-01-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.
Acta Crystallogr.,Sect.D, 68, 2012
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2C0J
 | | Crystal structure of the bet3-trs33 heterodimer | | Descriptor: | PALMITIC ACID, R32611_2, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 | | Authors: | Kim, M.-S, Yi, M.-J, Lee, K.-H, Wagner, J, Munger, C, Kim, Y.-G, Whiteway, M, Cygler, M, Oh, B.-H, Sacher, M. | | Deposit date: | 2005-09-03 | | Release date: | 2006-02-07 | | Last modified: | 2015-01-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Biochemical and Crystallographic Studies Reveal a Specific Interaction between Trapp Subunits Trs33P and Bet3P
Traffic, 6, 2005
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6AQ7
 | | Structure of POM6 FAB fragment complexed with mouse PrPc | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ... | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2017-08-18 | | Release date: | 2018-04-04 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.
FEBS J., 285, 2018
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4YXH
 | | Crystal structure of Deer prion protein complexed with POM1 FAB | | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2015-03-23 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXK
 | | Crystal structure of Elk prion protein complexed with POM1 FAB | | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2015-03-23 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.805 Å) | | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YX2
 | | Crystal structure of Bovine prion protein complexed with POM1 FAB | | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2015-03-22 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.194 Å) | | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXL
 | | Crystal structure of Syrian hamster prion protein complexed with POM1 FAB | | Descriptor: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2015-03-23 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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2A1H
 | | X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin | | Descriptor: | ACETIC ACID, PYRIDOXAL-5'-PHOSPHATE, [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID, ... | | Authors: | Goto, M, Miyahara, I, Hirotsu, K, Conway, M, Yennawar, N, Islam, M.M, Hutson, S.M. | | Deposit date: | 2005-06-20 | | Release date: | 2005-09-06 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.
J.Biol.Chem., 280, 2005
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2DPK
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1X9X
 | | Solution Structure of Dimeric SAM Domain from MAPKKK Ste11 | | Descriptor: | Serine/threonine-protein kinase STE11 | | Authors: | Bhattacharjya, S, Xu, P, Gingras, R, Shaykhutdinov, R, Wu, C, Whiteway, M, Ni, F. | | Deposit date: | 2004-08-24 | | Release date: | 2005-08-30 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex.
J.Mol.Biol., 344, 2004
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4MA7
 | | Crystal structure of mouse prion protein complexed with Promazine | | Descriptor: | Major prion protein, POM1 heavy chain, POM1 light chain, ... | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2013-08-15 | | Release date: | 2014-01-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
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4H88
 | | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | | Descriptor: | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... | | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | | Deposit date: | 2012-09-21 | | Release date: | 2013-07-31 | | Last modified: | 2013-09-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Nature, 501, 2013
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4MA8
 | | Crystal structure of mouse prion protein complexed with Chlorpromazine | | Descriptor: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Major prion protein, POM1 heavy chain, ... | | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | | Deposit date: | 2013-08-15 | | Release date: | 2014-01-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
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1EKV
 | | HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL): THREE DIMENSIONAL STRUCTURE OF ENZYME INACTIVATED BY TRIS BOUND TO THE PYRIDOXAL-5'-PHOSPHATE ON ONE END AND ACTIVE SITE LYS202 NZ ON THE OTHER. | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K. | | Deposit date: | 2000-03-09 | | Release date: | 2001-03-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
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1EKP
 | | CRYSTAL STRUCTURE OF HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL) COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE AT 2.5 ANGSTROMS (MONOCLINIC FORM). | | Descriptor: | BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K. | | Deposit date: | 2000-03-09 | | Release date: | 2001-03-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
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4TLU
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4TNG
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4TNF
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1EKF
 | | CRYSTALLOGRAPHIC STRUCTURE OF HUMAN BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL) COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE AT 1.95 ANGSTROMS (ORTHORHOMBIC FORM) | | Descriptor: | BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE (MITOCHONDRIAL), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Yennawar, N.H, Dunbar, J.H, Conway, M, Hutson, S.M, Farber, G.K. | | Deposit date: | 2000-03-08 | | Release date: | 2001-03-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The structure of human mitochondrial branched-chain aminotransferase.
Acta Crystallogr.,Sect.D, 57, 2001
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