4MA8
Crystal structure of mouse prion protein complexed with Chlorpromazine
Summary for 4MA8
Entry DOI | 10.2210/pdb4ma8/pdb |
Related | 4MA7 |
Descriptor | Major prion protein, POM1 heavy chain, POM1 light chain, ... (5 entities in total) |
Functional Keywords | immunoglobulin fold, fab, antibody, mouse prion protein, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor (By similarity): P04925 |
Total number of polymer chains | 3 |
Total formula weight | 60586.52 |
Authors | Baral, P.K.,Swayampakula, M.,James, M.N.G. (deposition date: 2013-08-15, release date: 2014-01-22, Last modification date: 2023-09-20) |
Primary citation | Baral, P.K.,Swayampakula, M.,Rout, M.K.,Kav, N.N.,Spyracopoulos, L.,Aguzzi, A.,James, M.N. Structural basis of prion inhibition by phenothiazine compounds. Structure, 22:291-303, 2014 Cited by PubMed: 24373770DOI: 10.1016/j.str.2013.11.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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