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4MA7

Crystal structure of mouse prion protein complexed with Promazine

Summary for 4MA7
Entry DOI10.2210/pdb4ma7/pdb
Related4MA8
DescriptorMajor prion protein, POM1 heavy chain, POM1 light chain, ... (5 entities in total)
Functional Keywordsimmunoglobulin fold, fab, antibody, mouse prion protein, immune system
Biological sourceMus musculus (mouse)
More
Cellular locationCell membrane; Lipid-anchor, GPI-anchor (By similarity): P04925
Total number of polymer chains3
Total formula weight60552.08
Authors
Baral, P.K.,Swayampakula, M.,James, M.N.G. (deposition date: 2013-08-15, release date: 2014-01-22, Last modification date: 2023-09-20)
Primary citationBaral, P.K.,Swayampakula, M.,Rout, M.K.,Kav, N.N.,Spyracopoulos, L.,Aguzzi, A.,James, M.N.
Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22:291-303, 2014
Cited by
PubMed: 24373770
DOI: 10.1016/j.str.2013.11.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.97 Å)
Structure validation

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