4TLU

Crystal Structure of Human Transthyretin Ala108Trp Mutant

Summary for 4TLU

Related4TKW 4TL4 4TL5 4TLK 4TLS 4TLT 4TM9 4TNE 4TNF 4TNG
DescriptorTransthyretin, CHLORIDE ION (3 entities in total)
Functional Keywordshuman transthyretin, amyloid, transthyretin, mutant, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationSecreted P02766
Total number of polymer chains2
Total molecular weight28200.86
Authors
Saelices, L.,Cascio, D.,Sawaya, M.,Eisenberg, D.S. (deposition date: 2014-05-30, release date: 2015-12-30, Last modification date: 2017-11-22)
Primary citation
Saelices, L.,Cascio, D.,Sawaya, M.,Eisenberg, D.S.
Crystal Structure of Human Transthyretin Ala108Trp Mutant
to be published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2095004.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12