4J8R

Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment

Summary for 4J8R

• Entry DOI: 10.2210/pdb4j8r/pdb
• Descriptor: Light chain of POM2 Fab, Heavy chain of POM2 Fab, Major prion protein, ... (4 entities in total)
• Functional Keywords: immunoglobulin fold, fab, antibody, octapeptide repeat, mouse prion protein, immune system
• Biological source: Mus musculus; More
• Cellular location: Cell membrane ; Lipid-anchor, GPI-anchor : P04925
• Total number of polymer chains: 6
• Total formula weight: 95912.38

Authors

Swayampakula, M.,Baral, P.K.,Kav, N.N.V.,Aguzzi, A.,James, M.N.G. (deposition date: 2013-02-14, release date: 2013-05-22, Last modification date: 2023-09-20)

• Primary citation: Swayampakula, M.,Baral, P.K.,Aguzzi, A.,Kav, N.N.,James, M.N.; The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.; Protein Sci., 22:893-903, 2013; PubMed: 23629842; DOI: 10.1002/pro.2270

Experimental method

X-RAY DIFFRACTION (2.303 Å)