4XHQ
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6CO3
| aducanumab abeta complex | 分子名称: | ALA-GLU-PHE-ARG-HIS-ASP, Fab heavy chain, Fab light chain, ... | 著者 | Arndt, J.W. | 登録日 | 2018-03-10 | 公開日 | 2018-05-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.384 Å) | 主引用文献 | Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta. Sci Rep, 8, 2018
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3V4P
| crystal structure of a4b7 headpiece complexed with Fab ACT-1 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yu, Y, Zhu, J, Springer, T.A. | 登録日 | 2011-12-15 | 公開日 | 2012-01-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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3V4V
| crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yu, Y, Zhu, J, Springer, T.A. | 登録日 | 2011-12-15 | 公開日 | 2012-01-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion J.Cell Biol., 196, 2012
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5I05
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3D1D
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3D1B
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3OQ9
| Structure of the FAS/FADD death domain assembly | 分子名称: | Protein FADD, Tumor necrosis factor receptor superfamily member 6 | 著者 | Kabaleeswaran, V, Wu, H. | 登録日 | 2010-09-02 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (6.8 Å) | 主引用文献 | The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations. Nat.Struct.Mol.Biol., 17, 2010
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3E0G
| Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leukemia inhibitory factor receptor, ... | 著者 | Lupardus, P.J, Garcia, K.C. | 登録日 | 2008-07-31 | 公開日 | 2008-09-23 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol.Cell, 31, 2008
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1Y12
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8FWF
| Crystal structure of Apo form Fab235 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-21 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FXJ
| Crystal structure of Fab460 | 分子名称: | ACETATE ION, CHLORIDE ION, Fab460, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-24 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FYM
| Crystal structure of Fab235 in complex with MPER peptide | 分子名称: | ALA-SER-LEU-TRP-ASN-TRP-PHE-ASN-ILE-THR-ASN-TRP-LEU-TRP-TYR-ILE-LYS-LYS-LYS, CHLORIDE ION, Fab235, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-26 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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8FZ2
| Crystal structure of Fab460 in complex with MPER peptide | 分子名称: | Fab460, H chain, L chain, ... | 著者 | Tan, K, Kim, M, Reinherz, E.L. | 登録日 | 2023-01-27 | 公開日 | 2023-10-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility. Nat Commun, 14, 2023
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3HND
| Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP and substrate GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... | 著者 | Fairman, J.W, Wijerathna, S.R, Xu, H, Dealwis, C.G. | 登録日 | 2009-05-31 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
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3HNC
| Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP | 分子名称: | MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, SULFATE ION, ... | 著者 | Fairman, J.W, Wijerathna, S.R, Xu, H, Dealwis, C.G. | 登録日 | 2009-05-31 | 公開日 | 2011-02-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
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3HNF
| Crystal structure of human ribonucleotide reductase 1 bound to the effectors TTP and dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... | 著者 | Fairman, J.W, Wijerathna, S.R, Xu, H, Dealwis, C.G. | 登録日 | 2009-05-31 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
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3HNE
| Crystal structure of human ribonucleotide reductase 1 bound to the effectors TTP and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... | 著者 | Fairman, J.W, Wijerathna, S.R, Xu, H, Dealwis, C.G. | 登録日 | 2009-05-31 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
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5TRC
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4L5T
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4L5R
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4L5Q
| Crystal structure of p202 HIN1 | 分子名称: | Interferon-activable protein 202 | 著者 | Yin, Q, Tian, Y, Wu, H. | 登録日 | 2013-06-11 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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4L5S
| p202 HIN1 in complex with 12-mer dsDNA | 分子名称: | 12-mer DNA, Interferon-activable protein 202, SULFATE ION | 著者 | Yin, Q, Tian, Y, Wu, H. | 登録日 | 2013-06-11 | 公開日 | 2013-08-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
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3PAW
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3RJR
| Crystal Structure of pro-TGF beta 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta-1 | 著者 | Zhu, J.H, Shi, M.L, Springer, T.A. | 登録日 | 2011-04-15 | 公開日 | 2011-06-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Latent TGF-Beta structure and activation Nature, 474, 2011
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