6CO3
aducanumab abeta complex
Summary for 6CO3
Entry DOI | 10.2210/pdb6co3/pdb |
Descriptor | Fab light chain, Fab heavy chain, ALA-GLU-PHE-ARG-HIS-ASP, ... (5 entities in total) |
Functional Keywords | antibody fab fragment, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 49026.63 |
Authors | Arndt, J.W. (deposition date: 2018-03-10, release date: 2018-05-02, Last modification date: 2023-10-04) |
Primary citation | Arndt, J.W.,Qian, F.,Smith, B.A.,Quan, C.,Kilambi, K.P.,Bush, M.W.,Walz, T.,Pepinsky, R.B.,Bussiere, T.,Hamann, S.,Cameron, T.O.,Weinreb, P.H. Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta. Sci Rep, 8:6412-6412, 2018 Cited by PubMed: 29686315DOI: 10.1038/s41598-018-24501-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.384 Å) |
Structure validation
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