3OQ9

Structure of the FAS/FADD death domain assembly

Summary for 3OQ9

• Entry DOI: 10.2210/pdb3oq9/pdb
• Descriptor: Tumor necrosis factor receptor superfamily member 6, Protein FADD (2 entities in total)
• Functional Keywords: apoptosis, disc, fas, fadd
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P25446
• Total number of polymer chains: 10
• Total formula weight: 109239.28

Authors

Kabaleeswaran, V.,Wu, H. (deposition date: 2010-09-02, release date: 2010-10-13, Last modification date: 2024-02-21)

• Primary citation: Wang, L.,Yang, J.K.,Kabaleeswaran, V.,Rice, A.J.,Cruz, A.C.,Park, A.Y.,Yin, Q.,Damko, E.,Jang, S.B.,Raunser, S.,Robinson, C.V.,Siegel, R.M.,Walz, T.,Wu, H.; The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.; Nat.Struct.Mol.Biol., 17:1324-1329, 2010; PubMed: 20935634; DOI: 10.1038/nsmb.1920

Experimental method

X-RAY DIFFRACTION (6.8 Å)