3OQ9

Structure of the FAS/FADD death domain assembly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Tumor necrosis factor receptor superfamily member 6	polymer	86	10162.7	5	UniProt (P25446) Pfam (PF00531)	Mus musculus (mouse)	FASLG receptor, Apoptosis-mediating surface antigen FAS, Apo-1 antigen
2	F, G, H, I, J (H, I, J, K, L)	Protein FADD	polymer	100	11685.2	5	UniProt (Q13158) Pfam (PF00531)	Homo sapiens (human)	FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein

Sequence modifications

H, I, J, K, L: 93 - 184 (UniProt: Q13158)

PDB	External Database	Details
Leu 185	-	expression tag
Glu 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	109239.3
All*	Total formula weight	109239.3

*Water molecules are not included.